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U-GEMMs

About 42,431 results
Mice

R26-CAG-LSL-hEML4/ALK*F1174L-Luc-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-EML4-ALK(F1174L)-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190010

A SA-2xpolyA-CAG-LSL-EML4-ALK(F1174L)-IRES-Luciferase-2A-tdTomato-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the EML4-ALK(F1174L) protein.

Mice

Pnliprp1-KO

Strain Name：B6;129S-Pnliprp1tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00005

Exon 1 to exon 8 were replaced with Neo cassette.

Mice

R26-ZsGreen,-DTA

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm(CAG-ZsGreen,-DTA)1Smoc
Strain State：Developing | Cat. NO.：NM-KI-225002

CAG-zsGreen-DTA expression cassette was knocked into the the Rosa26 locus.

Mice

MHC Class II (I-A/I-E) -KO

Strain Name：C57BL/6Smoc-H2-Ab1em1H2-Aaem1 H2-Eb1em1H2-Eb2em1H2-Ea-ps em1 Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18032

All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models. These MHC class II molecule-deficient mice were on the C57BL/6J genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins.

Mice

hIL1RAP

Strain Name：C57BL/6Smoc-Il1raptm3(hIL1RAP)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000070

The endogenous mouse Il1rap gene was replaced by human IL1RAP gene.

Mice

hCD37

Strain Name：C57BL/6Smoc-Cd37em1(hCD37)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225029

The endogenous mouse Cd37 gene was replaced by human CD37 gene.

Mice

Wt1-GFPCre

Strain Name：C57BL/6Smoc-Wt1em1(GFPCre-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200128

A GFPCre-WPRE-pA expression cassette was knocked into the Wt1 gene start codon site.

Mice

Cd19-2A-DreERT2

Strain Name：C57BL/6Smoc-Cd19em(2A-DreERT2-Wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-215084

2A-DreERT2-Wpre-pA expression cassette was knocked into the Cd19 gene .

Mice

R26-CAG-LSL-hPIK3CA*H1047R-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-PIK3CA(H1047R)-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190065

These mice harbor a CAG-LSL-PIK3CA(H1047R)-IRES-luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

Mice

hIL10

Strain Name：C57BL/6Smoc-Il10tm4(hIL10)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000063

The endogenous mouse Il10 gene was replaced by human IL10 gene.

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