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U-GEMMs

About 42,431 results
Mice

hTHPO

Strain Name：C57BL/6Smoc-Thpotm1(hTHPO)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000062

The endogenous mouse Thpo gene was replaced by human THPO gene.

Mice

hCTLA-4(2)

Strain Name：C57BL/6Smoc-Ctla4em2(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190038

Extracellular domain of mouse Ctla4 gene was replaced by human CTLA4 gene. While hCTLA4(Stock No.NM-HU-00014) mice function similarly to hCTLA4(2) mice,for more detailed information please contact our technical advisor.

Mice

Il23a-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il23aem1(Luc-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00057

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il23a.

Mice

Abcd4-KO

Strain Name：C57BL/6Smoc-Abcd4em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-2110692

Exon 2-13 of Abcd4 gene was deleted to generate Abcd4 knockout mice.

Mice

Nos3-KO

Strain Name：C57BL/6Smoc-Nos3em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18022

Exon10-11 of Nos3 gene were deleted to generate Nos3 knockout mice.

Mice

hPD-1/hPD-L1/hLAG3

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Lag3em1(hLAG3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190028

hPD-1(NM-HU-00015),hPD-L1(NM-HU-00062) were crossed with hLAG3(NM-HU-00049) to generate hPD-1/hPD-L1/hLAG3.

Mice

hPTGDR2

Strain Name：C57BL/6Smoc-Ptgdr2em1(hPTGDR2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-225033

The endogenous mouse Ptgdr2 gene was replaced by human PTGDR2 gene.

Mice

R26-loxP-tdTomato-loxP-DTA

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm(SA-loxP-tdTomato-PGK-Neo-3xpA-loxP-DTA-pA)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225003

SA-loxP-tdTomato-PGK-Neo-3xpA-loxP-DTA-pA expression cassette was knocked into the the Rosa26 locus.

Mice

Lmna-c.C1827T

Strain Name：C57BL/6Smoc-Lmnaem1(G609G)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200284

These mice carry a G609G mutation of Lmna gene.

Mice

Mc4r-2A-Cre

Strain Name：C57BL/6Smoc-Mc4rem1(T2A-Cre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200220

A T2A-Cre expression cassette was knocked into the Mc4r gene stop codon site.

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