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Models

About 43,983 results
Mice

hKLRK1

Strain Name：C57BL/6Smoc-Klrk1em1(hKLRK1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190005
Validation Data：Presence

The endogenous mouse Klrk1 gene was replaced by human KLRK1 gene.

Mice

Ins2-DreERT2

Strain Name：C57BL/6Smoc-Ins2em2(DreERT2-Wpre-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190039
Validation Data：Absence

A DreERT2-Wpre-polyA expression cassette was knocked into initiation codon ATG site of the Ins2 gene.

Mice

hLAG3/hCTLA-4

Strain Name：B6.129S-Lag3em1(hLAG3)Ctla4em1(hCTLA4)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190018
Validation Data：Absence

This LAG3 and CTLA4 double knockin strain is established by crossing LAG3-HU and CTLA4-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hIL21/hIL21R

Strain Name：C57BL/6Smoc-Il21tm1(hIL21)Il21rtm1(hIL21R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220038
Validation Data：Presence

hIL21(NM-HU-200255) were crossed with hIL21R(NM-HU-210031) to generate hIL21/hIL21R mice.

Mice

hMIF

Strain Name：C57BL/6Smoc-Mifem3(hMIF)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000030
Validation Data：Absence

The endogenous mouse Mif gene was replaced by human MIF gene.

Mice

hCD3EDG/hCD28/hCD38(2)

Strain Name：C57BL/6Smoc-Cd3eem1(hCD3E)Cd3dem1(hCD3D)Cd3gem1(hCD3G)Cd28em2(hCD28)Cd38em2(hCD38)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220115
Validation Data：Absence

hCD3EDG/hCD28(NM-HU-220113) mice were crossed with hCD3EDG/hCD38(NM-HU-220114) mice to generate hCD3EDG/hCD28/hCD38(2) mice.

Mice

hPLK1

Strain Name：C57BL/6Smoc-Plk1em1(hPLK1)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-225083
Validation Data：Absence

The endogenous mouse Plk1 gene was replaced by human PLK1 gene.

Mice

Npr3-2A-DreERT2

Strain Name：C57BL/6Smoc-Npr3em1(2A-DreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190015
Validation Data：Presence

The 2A-DreERT2 cassette is inserted before 3'UTR region of Npr3 gene.

Mice

Crh-IRES-Cre

Strain Name：C57BL/6Smoc-Crhem1(IRES-iCre-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200104
Validation Data：Absence

A IRES-iCre-pA expression cassette was knocked into the Crh gene stop codon site. This strain exhibits ectopic expression, and its expression profile requires validation.

Mice

Lrp1-Flox

Strain Name：C57BL/6Smoc-Lrp1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-2101319
Validation Data：Absence

These mice carry loxP sites flanking exon 7-8 of Lrp1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Lrp1 gene.

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