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Imaging Analysis

Animal imaging micro CT

shanghai Model Organisms provides services for microCT and IVIS whole-body in vivo imaging/fluorescence quantitative analysis of small animals.

Pathological Analysis

Pathological analysis H&E staining

Shanghai Model Organisms can analyze morphological and pathological changes in various animal tissues.

Gene Expression/Protein Analysis

protein expression analysis Gene expression analysis

Shanghai Model Organisms provides high-quality gene and protein expression analysis services, including RT-PCR, real time PCR, and Western blot, with accurate experimental results that can be used for publication.

Behavioral Analysis

study of animal behavior behavioral analysis

Shanghai Model Organisms' rodent behavioral analysis platform is equipped with a variety of experimental instruments used to study the classical behaviors of mice. Shanghai Model Organisms can provide single-item or complete sets of mouse behavioral analysis to assist you with your research in neurology, physiology, drug development, and drug efficacy evaluation. The Noldus behavioral analysis system is used to more comprehensively and accurately reflect the neurological and mental states of mice.

약물 효과 분석 및 평가

Shanghai Model Organisms Center, Inc.(사)는 약물 효과 평가 서비스는 U-GEMMs 리소스 라이브러리를 기반으로 하여 항염 면역, 항종양, 심혈관계, 호흡계, 대사성 질병 등 약물의 주요 약력학 연구를 수행할 수 있으며, 체내 실험, 메커니즘 검토 및 분자생물학 연구 등 서로 다른 수준의 연구 수요를 충족시켜 신약의 유효성과 안전성을 확립하고 국내외의 제약업체, 생물의학연구소, 신약개발센터, 고등교육기관의 신약 연구개발 기관 등에 전문적인 약력학 평가 서비스를 제공합니다.

Blood Analysis

Mouse serum mouse serum albumin

At Shanghai Model Organisms Center, we use an automatic biochemical analyzer to measure a specific chemical composition of serum according to the principle of photoelectric colorimetry. This can be used to assess liver and kidney functions or measure blood sugar, blood lipids, and electrolytes.

Drug Screening

drug screening high throughput screening for drug discovery

With a comprehensive model organisms service platform that generates the mouse, zebrafish and C. elegans models, Shanghai Model Organisms enables high-throughput drug screening as well as the evaluation and research on drug efficacy, thus accelerating drug development and achieving greater accuracy in the prediction of in vivo interactions.

薬効の分析と評価

上海南方モデル動物バイオテクノロジー株式会社（Shanghai Model Organisms Center, Inc）の薬力学的評価サービスは、二十年の業界経験を積み重ねて、自社開発のU-GEMM®モデルマウスリソースライブラリーを利用して、抗炎免疫、抗腫瘍、心臓血管系、呼吸器系、代謝性疾患など薬物のスクリーニングをする為に、研究者様の求めに応じて 、in vivo 実験、メカニズムの検討、分子生物学研究などの異なるレベルの研究ニーズを満足し、新薬の有効性と安全性を明らかにし、国内外の製薬会社、生物医薬研究機関、新薬開発センター、大学の新薬開発機関などに、専門的な薬力学的評価サービスを提供しております。

Pharmacodynamics Analysis & Evaluation

Based on the U-GEMM repository, the pharmacodynamics evaluation service from Shanghai Model Organisms can conduct main pharmacodynamics study on the drugs for anti-inflammatory-immunity, antineoplastic, cardiovascular system, respiratory system and metabolic diseases,etc, satisfy the study requirements of different layers of in vivo experiments, mechanism investigation and molecular biological study, and confirm the effectiveness and safety of new drug(s).

Osteoporosis

osteoporosis gene osteoporosis diseases Tnfrsf11b

Tnfrsf11b (Opg) knockout mice were generated through homologous recombination and supplied by Shanghai Research Center for Model Organisms. This mouse model, which is referred to as the "osteoporotic mouse", shows a typical phenotype of osteoporosis and arterial calcification, and Therefore, this animal model is ideal for drug screening and evaluation for the treatment of "human osteoporosis", in gene therapy of osteoporosis, as well as in the research on the mechanisms of interaction between osteoclasts and osteoblasts.