Tumor Targets

Humanized tumor target mice are immunocompetent chimeric mouse models, engineered to express humanized tumor targets such as genes encoding for oncogene proteins, tumor suppressor proteins, tumor specific antigen, etc. These models can can be used to evaluate the risk of on-target, off-tumor toxicities for targeted cancer drug.

mouse	hMERTK Strain Name：C57BL/6JSmo-Mertk^{tm1(hMERTK)/Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-2000031 Research Application：Immunotherapy,drug screening
mouse	hMIEN1 Strain Name：C57BL/6JSmo-Mien1^{tm1(hMIEN1)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-200246
mouse	hMSLN-TG Strain Name：C57BL/6JSmo-Tgtn(hMSLN)1Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-TG-225014
mouse	hMUC1 Strain Name：C57BL/6JSmo-Muc1^{tm(hMUC1)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-220409
mouse	hMUC1-c.462insC Strain Name：C57BL/6JSmo-Muc1^{tm(hMUC1-c.462insC)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-220410
mouse	hNCR2-TG Strain Name：C57BL/6JSmo-Tgtn(hNCR2)1Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-TG-225019
mouse	hNCR3-TG Strain Name：C57BL/6JSmo-Tgtn(hNCR3)1Smoc Strain State：Developing \| Cat. NO.：NM-TG-225018
mouse	hNECTIN4 Strain Name：C57BL/6JSmo-Nectin4^{tm1(hNECTIN4)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-210016 Research Application：drug screening
mouse	hNR3C1 Strain Name：C57BL/6JSmo-Nr3c1^{tm1(hNR3C1)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-HU-225058
mouse	hNTRK1 Strain Name：C57BL/6JSmo-Ntrk1^{tm(hNTRK1)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-230058

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