hNTRK1

Nomenclature

C57BL/6Smoc-Ntrk1em(hNTRK1)Smoc

Cat. NO.

NM-HU-230058

Strain State

Repository Live

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Gene Summary

Gene Symbol
Ntrk1

Model Description

The endogenous mouse Ntrk1 gene was replaced by human NTRK1 gene.

Validation Data

image.png

Fig.1 Detection of NTRK1 expression in adrenal by RT-PCR. 

Wild type: only one band at 146 bp with primers F1/R1(mNtrk1);

Homozygous:  only one band at 148 bp with primers F2/R2(hNTRK1). 

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human NTRK1 expression in hNTRK1 knockin mice by WB. 

Abbr. M, marker; WT, wild type; HO, Homozygous; PC, positive control, MCF-7 cells.

Note. The anti-human NTRK1 antibody cross-reacted with mouse NTRK1 and humanized NTRK1.



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