Csf2-KO

Nomenclature

C57BL/6Smoc-Csf2em2Smoc

Cat. NO.

NM-KO-190532

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
CSF2

Model Description

Exon 1-3 of Csf2 gene was deleted to generate Csf2 knockout mice. Homozygotes for targeted null mutations exhibit lung abnormalities with lymphocytic infiltration and accumulation of surfactant lipids. Litter sizes from homozygous breeding pairs are smaller at weaning due to perinatal mortality (Note from MGI).
Research Application:Growth Factors,NF-KB pathway,Allergy and Asthma,

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