Models

Knockouts

Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.

mouse
Strain Name:C57BL/6JSmo-Gabbr2em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190960
Research Application:Nervous system, thermal or mechanical stimulation of epilepsy, pain, anxiety and depression
mouse
Strain Name:C57BL/6JSmo-Gabpaem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-210269
mouse
Strain Name:C57BL/6Smoc-Gabpb2em1Smoc
Strain State:Developing | Cat. NO.:TBD
mouse
Strain Name:C57BL/6JSmo-Gabra1em1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-190570
Research Application:Epilepsy research related
mouse
Strain Name:C57BL/6JSmo-Gabra3em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200212
Research Application:Therapeutic antibody target
mouse
Strain Name:C57BL/6JSmo-Gabra4em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-190572
Research Application:Autism research related
mouse
Strain Name:C57BL/6JSmo-Gabra5em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-190573
mouse
Strain Name:C57BL/6JSmo-Gabra6em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190574
mouse
Strain Name:C57BL/6JSmo-Gabrb1em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190575
Research Application:Related to schizophrenia research
mouse
Strain Name:C57BL/6Smoc-Gabrb2em1Smoc
Strain State:Developing | Cat. NO.:TBD
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