hFCRN(NOD-scid)

Nomenclature

NOD-PrkdcscidFcgrtem2(FCGRT)Smoc

Cat. NO.

NM-HU-200006

Strain State

Repository Live

Export PDF

Gene Summary

Gene Symbol
Fcgrt

Synonyms

FcRn

NCBI ID

14132

MGI ID

103017

Ensembl ID

ENSMUSG00000003420

Pubmed

Fcgrt

Human Ortholog

FCGRT

Model Description

The endogenous mouse Fcgrt gene was replaced by human FCGRT gene (NOD-scid background).
Research Application：Immunotherapy,cancer research,drug screening

Validation Data

image.png

Fig.1 Detection of FCGRT expression in kidney by RT-PCR. 

Wild type: only one band at 181 bp with primers F1/R1(mFcgrt);

Heterozygous: one band at 181 bp with primers F1/R1(mFcgrt) and one band at 310 bp with primers F2/R2(hFCGRT). 

Abbr. M, DNA marker; HE, heterozygous; WT, wild type.

image.png

Fig.2 Detection of human FCGRT expression in hFCGRT (Nod-SCID) mice by WB. 

Abbr. M, marker; WT1, wild type, Nod-SCID; WT2, wild type, M-NSG; HE, heterozygous; PC, positive control, hFCGRT(NM-HU-190070).

You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more