hIL3-hCSF2-Tg(NMG)
Nomenclature
NOD-PrkdcscidIl2rgem1Tg(hIL3-hCSF2)Smoc
Cat. NO.
NM-KI-215006
Strain State
Sperm cryopreservation
Model Description
Validation Data
Fig.1 Detection of hCSF2(A) and hIL3(B) expression in serum by ELISA(n=3).
Abbr. HO, homozygous; N.D. not detected.
Fig. 2 Human immune cell phenotyping in hIL3-hCSF2-transgenic (NMG) engrafted with human HSCs. Human CD34+ cells (1.0×10^5) were intravenously injected into homozygous hIL3-hCSF2-transgenic (NMG) pretreated with 1.0 Gy irradiation. These results demonstrate successful engraftment and propagation of human T, B, Myeloid and Momocytescells in the hIL3-hCSF2-transgenic (NMG) model.
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