hIL18

Nomenclature

C57BL/6Smoc-Il18tm1(hIL18)Smoc

Cat. NO.

NM-HU-210038

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Il18

Synonyms

Igif; Il-18

NCBI ID

16173

MGI ID

107936

Ensembl ID

ENSMUSG00000039217

Pubmed

Il18

Human Ortholog

IL18

Model Description

The endogenous mice Il18 gene was replaced by human IL18 gene.
Research Application：inmmue therapy；drug screening

Validation Data

image.png

Fig1. Detection of IL18 expression in intestine, colon and spleen by RT-PCR. 

Wild type: only one band at 305 bp with primers F1/R1 (mIl18); Homozygous: only one band at 265 bp with primers F2/R2 (hIL18). 

Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig2. Detection of hIL18 expression in serum by ELISA (n=3). 

Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig3. Detection of mIL18 expression in serum by ELISA (n=3). 

Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

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