hIL31

Nomenclature

C57BL/6Smoc-Il31em2(IL31)Smoc

Cat. NO.

NM-HU-200008

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Il31

Model Description

The endogenous mouse Il31 gene was replaced by human IL31 gene.
Research Application:Immunotherapy,cancer research,drug screening

Validation Data

image.png

Fig.1 Detection of IL31 expression in testis by RT-PCR. 

Wild type: only one band at 166 bp with primers F1/R1(mIl31);

Homozygous: only one band at 332 bp with primers F2/R2(hIL31).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human IL31 expression in splenocyte in hIL31 mice by WB. 

Abbr. M, marker; WT, wild type; HO, Homozygous.

Note. The anti-human IL31 antibody cross-reacted with mouse IL31 and humanized IL31.




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