hIL4

Nomenclature

C57BL/6Smoc-Il4tm3(hIL4)Smoc

Cat. NO.

NM-HU-190071

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Il4

Model Description

The endogenous mouse Il4 gene was completely or partially replaced by human IL4 gene via ESC targeting.

Research Application:Immunotherapy,cancer research,drug screening

Validation Data

image.png

Fig1. Detection of IL4 expression by RT-PCR. 

Wild type: only one band at 254 bp with primers F2/R2(mIl4);

Homozygous: only one band at 247 bp with primers F1/R1(hIL4); 

Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.


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