hIL3/hCSF2

Nomenclature

C57BL/6Smoc-Il3tm3(hIL3)Csf2tm3(hCSF2)/Smoc

Cat. NO.

NM-HU-190065

Strain State

Repository Live

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Gene Summary

Gene Symbol
IL3

Synonyms

BPA; PSF; HCGF; Il-3; MCGF; Csfmu

NCBI ID

16187

MGI ID

96552

Ensembl ID

ENSMUSG00000018914

Pubmed

IL3

Human Ortholog

IL3

Gene Symbol
CSF2

Synonyms

CSF; Csfgm; GMCSF; Gm-CSf; MGI-IGM

NCBI ID

12981

MGI ID

1339752

Ensembl ID

ENSMUSG00000018916

Pubmed

CSF2

Human Ortholog

CSF2

Model Description

The endogenous mouse Il3 and Csf2 gene was replaced by human IL3 and CSF2 gene.
Research Application：Immunotherapy,cancer research,drug screening

Validation Data

image.png

Fig.1 Detection of mCSF2(A) and hCSF2(B) expression in serum by ELISA(n=3). 

Abbr. HO, homozygous; WT, wild type; N.D. not detected

Note.hIL3/hCSF2 and C57BL/6 mice were i.p. injected with LPS for 2h.

image.png

Fig.2 Detection of mIL3(A) and hIL3(B) expression in splenocyte by ELISA(n=3). 

Abbr. HO, homozygous; WT, wild type; N.D. not detected.

Note. Splenocyte were stimulated with ConA and IL2 in vitro for 48h.


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