Models

Conditional Knockouts

In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.

Mice
Strain Name:C57BL/6JSmo-Fzd1em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-231777
Mice
Strain Name:C57BL/6JSmo-Fzd10tm1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-232179
Mice
Strain Name:C57BL/6Smoc-Fzd10osem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6JSmo-Fzd2em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-226439
Mice
Strain Name:C57BL/6Smoc-Fzd3em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6JSmo-Fzd4em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2116735
Mice
Strain Name:C57BL/6JSmo-Fzd5tm1(flox)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-CKO-200178
Research Application:Research on ERK signal and Wnt signal
Mice
Strain Name:C57BL/6JSmo-Fzd6em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2108735
Mice
Strain Name:C57BL/6JSmo-Fzd7tm1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-231234
Mice
Strain Name:C57BL/6Smoc-Fzd8em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Email Back to top