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U-GEMMs

About 42,431 results
Mice

Krt5-IRES-CreERT2

Strain Name：C57BL/6Smoc-Krt5em1(IRES-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200168

A IRES-CreERT2 expression cassette was knocked into the Krt5 gene stop codon site.

Mice

hPD-1/hPD-L1/hCD73(2)

Strain Name：C57BL/6Smoc-Pdcd1em1(hPD-1)Cd274em1(hPD-L1)Nt5eem2(hNT5E)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210410

hPD-1(NM-HU-00015) was crossed with hPD-L1/hCD73(2)(NM-HU-210356) to generate hPD-1/hPD-L1/hCD73(2) mice.

Mice

Ptf1a-CreERT2

Strain Name：C57BL/6Smoc-Ptf1aem1(CreERT2-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200118

A CreERT2-WPRE-pA expression cassette was knocked into the Ptf1a gene start codon site.

Mice

hPD-1/hVEGFR2

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Kdrtm2(hKDR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000098

hPD-1(NM-HU-00015) was crossed with hKDR(NM-HU-00098) to generate hPD-1/hKDR.

Mice

hCXCR6

Strain Name：C57BL/6Smoc-Cxcr6em(hCXCR6)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215001

The endogenous mice Cxcr6 gene was replaced by human CXCR6 gene.

Mice

Karma-2A-tdTomato-2A-DTR

Strain Name：C57BL/6Smoc-Gpr141bem1(2A-tdTomato-2A-DTR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210116

2A-tdTomato-2A-DTR expression cassette was knocked into the Karma gene.

Mice

Etv1-CreERT2

Strain Name：C57BL/6Smoc-Etv1em1(CreERT2-SV40-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200105

A CreERT2 expression cassette was knocked into the Etv1 gene start codon site. ETV1 expression is enriched in fast conduction tissues of embryonic and adult mammalian hearts. And ETV1 expression is upregulated in the atrial tissue of patients with permanent atrial fibrillation. Etv-CreERT2 mice can be applied to heart disease research. ETV1 is also expressed in retinal ganglion cells of adult mice, and the mouse model can be used to study how retinal ganglion cells contribute to visual processing in the brain.

Mice

Ifng-KO

Strain Name：C57BL/6Smoc-Ifngem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200723

Ifng-KO mice(Stock No.NM-KO-200723) carry a knockout allele derived from the targeted deletion of exon 1-4. While Ifng-KO(2) mice(Stock No.NM-KO-200873)carrying the exon 1 deletion.

Mice

Trp63-CreERT2

Strain Name：C57BL/6Smoc-Trp63em(CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225021

A CreERT2-Wpre-polyA expression cassette was knocked into the exon4 of Trp63 gene via CRISPR/Cas mediated recombination.

Mice

hNCR2

Strain Name：C57BL/6Smoc-Ncr1em1(hNCR2 )Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-215068

The endogenous mouse Ncr1 gene was replaced by human NCR2 gene.

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