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U-GEMMs

About 42,431 results
Mice

hCRLF2

Strain Name：C57BL/6Smoc-Crlf2tm1(hCRLF2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210028

The endogenous mice Crlf2 gene was completely or partially replaced by human CRLF2 gene via ESC targeting.

Mice

Plin1-2A-DreERT2

Strain Name：C57BL/6Smoc-Plin1em1(2A-DreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190034

A 2A-DreERT2 expression cassette was knocked into the Plin1 gene stop codon site.

Mice

hIL18BP

Strain Name：C57BL/6Smoc-Il18bpem1(hIL18BP)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210039

The endogenous mice Il18bp gene was replaced by human IL18BP gene.

Mice

R26-CAG-LSL-hEZH2*Y646N-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-EZH2(Y646N)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190073

These mice harbor a CAG-LSL-EZH2(Y646N)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

Mice

hIL6ST

Strain Name：C57BL/6Smoc-Il6stem1(hIL6ST)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204980

The endogenous mice Il6st gene was replaced by human IL6ST gene.

Mice

Upk3b-Dre

Strain Name：C57BL/6Smoc-Upk3bem1(Dre-Wpre-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200175

A Dre-Wpre-polyA expression cassette was knocked into the Upk3b gene start codon site.

Mice

Csf2rb2-2A-Cre

Strain Name：C57BL/6Smoc-Csf2rb2em1(2A-Cre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210001

2A-Cre expression cassette was knocked into the Csf2rb2 gene. Csf2rb2 is also known as colony stimulating factor 2 receptor. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. The gene product has been involved in the modulation of memory.

Mice

Fcgr2b-Fcgr3-Fcgr4-KO/hCTLA-4

Strain Name：C57BL/6Smoc-Fcgr2bem1Fcgr3em1Fcgr4em1Ctla4em1(hCTLA4)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-220069

The Fcgr2b-Fcgr3-Fcgr4-KO/hCTLA4 mouse model was obtained by deleting all sequences from upstream of Fcgr3 gene to the 3'UTR of Fcgr2b gene in the hCTLA4(NM-HU-00014) mouse.

Mice

AA467197-Flox

Strain Name：C57BL/6Smoc-AA467197em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of AA467197 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of AA467197 gene.

Mice

hMARCO

Strain Name：C57BL/6Smoc-Marcoem1(hMARCO)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000029

The endogenous mouse Marco gene was replaced by human MARCO gene.

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