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U-GEMMs

About 42,432 results
Mice

hTLR7

Strain Name：C57BL/6Smoc-Tlr7tm1(hTLR7)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18027

The endogenous mouse Tlr7 gene was replaced by humanTLR7  gene.

Mice

Rag2/IL2rg-KO/hCD40

Strain Name：C57BL/6Smoc-Cd40em1(hCD40)Rag2em1Il2rgem1/Smoc
Strain State：Developing | Cat. NO.：NM-HU-2000112

The Rag2 and Il2rg genes of the CD40 humanized mouse were deleted.

Mice

hC1QA

Strain Name：C57BL/6Smoc-C1qaem1(hC1QA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200282

The endogenous mice C1qa gene was replaced by human C1QA gene.

Mice

hC3

Strain Name：C57BL/6Smoc-C3em1(hC3)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000079

The endogenous mouse C3 gene was replaced by human C3 gene.

Mice

hTLR9

Strain Name：C57BL/6Smoc-Tlr9tm1(hTLR9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18016

This TLR9 humanized mouse model was established by replacing the mouse Tlr9 gene exon2 with the human TLR9 corresponding sequence by homologous recombination.

Mice

Krt14-CreERT2

Strain Name：C57BL/6Smoc-Krt14em2(CreERT2-Wpre-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190024

A  CreERT2-Wpre-polyA expression cassette was knocked into initiation codon ATG site of the Krt14 gene.

Mice

hOCLN

Strain Name：C57BL/6Smoc-Oclnem1(hOCLN)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190072

The endogenous mouse Ocln gene was replaced by human OCLN gene.

Mice

H11-CAG-LSL-mtagBFP2

Strain Name：C57BL/6Smoc-lgs2em1(CAG-LSL-mTagBFP2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190006

A CAG-LSL-mTagBFP2-3xFLAG-WPRE-polyA cassette was inserted at the mouse H11 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the mTagBFP2-3xFLAG protein.

Mice

hB2M-HLA A2.1(NMG,2)

Strain Name：NOD-PrkdcscidIl2rgem1B2mem1(hB2M-HLA A2.1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225090

The endogenous mouse B2m gene was replaced by human B2M-HLA A2.1 gene.

Mice

hCB1

Strain Name：C57BL/6Smoc-Cnr1em1(hCB1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225027

The endogenous mouse Cnr1 gene was replaced by human CB1 gene.

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