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Models

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Mice

Lgr5-EGFP-IRES-CreERT2

Strain Name：C57BL/6Smoc-Lgr5em1(EGFP-IRES-creERT2-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200154
Validation Data：Presence

A EGFP-IRES-creERT2-WPRE-polyA expression cassette was knocked into the Lgr5 gene start codon site.

Mice

Braf-Flox

Strain Name：C57BL/6Smoc-Brafem1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200073
Validation Data：Absence

These mice carry loxP sites flanking exon 5 of Braf gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Braf gene.

Mice

hC5

Strain Name：C57BL/6Smoc-Hcem1(hC5)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000013
Validation Data：Presence

The endogenous mouse C5a gene was replaced by human C5 gene.

Mice

hAPOC3

Strain Name：C57BL/6Smoc-Apoc3em1(hAPOC3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225050
Validation Data：Presence

The endogenous mouse Apoc3 gene was replaced by human APOC3 gene.

Mice

hCD19

Strain Name：C57BL/6Smoc-Cd19em1(hCD19) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00110
Validation Data：Presence

The endogenous mouse Cd19 gene was replaced by human CD19 gene .

Mice

hCD40

Strain Name：C57BL/6Smoc-Cd40em1(hCD40) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00076
Validation Data：Presence

The endogenous extracellular mouse Cd40 gene was replaced by the extracellular region of human CD40 gene.

Mice

Apoe-KO(2)

Strain Name：C57BL/6Smoc-Apoeem5Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190565
Validation Data：Presence

Apoe-KO(2) mice (Stock No.NM-KO-190565) carry a knockout allele derived from the targeted deletion of exon 2-4. While Apoe-KO mice (Stock No.NM-KO-00033) have been pulled from shelves for some reasons.

Mice

hCSF1

Strain Name：C57BL/6Smoc-Csf1em2(CSF1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190043
Validation Data：Presence

The endogenous mouse Csf1 gene was replaced by human CSF1 gene.

Mice

Rag2/IL2rg-KO/hVEGFR2

Strain Name：C57BL/6Smoc-Il2rgem1Kdrem2(hKDR)Rag2em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220087
Validation Data：Absence

IL2rg-KO (NM-KO-210098) mice were crossed with Rag2-KO/hKDR (NM-HU-200280) mice to generate Rag2/IL2rg-KO/hKDR mouse models.

Mice

B2m-KO

Strain Name：C57BL/6Smoc-B2mem3Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18021
Validation Data：Presence

Exon2-3 of B2m gene were deleted to generate Ifngr1 knockout mice.

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