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Models

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Mice

hCD19

Strain Name：C57BL/6JSmo-Cd19tm1(hCD19) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00110
Validation Data：Presence

The endogenous mouse Cd19 gene was replaced by human CD19 gene .

Mice

hCD28

Strain Name：C57BL/6JSmo-Cd28tm2(hCD28)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190011
Validation Data：Presence

The endogenous mouse Cd28 gene was replaced by human CD28 gene.

Mice

Lgr5-EGFP-IRES-CreERT2

Strain Name：C57BL/6JSmo-Lgr5em1(EGFP-IRES-creERT2-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200154
Validation Data：Presence

A EGFP-IRES-creERT2-WPRE-polyA expression cassette was knocked into the Lgr5 gene start codon site.

Mice

hCCR8(BALB/c)

Strain Name：BALB/cJSmo-Ccr8tm1(hCCR8)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000048
Validation Data：Presence

The endogenous mouse Ccr8 gene was replaced by human CCR8 gene.

Mice

hC1R

Strain Name：C57BL/6JSmo-C1raem1(hC1R)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-2000075
Validation Data：Presence

The endogenous mouse C1ra gene was replaced by human C1R gene.

Mice

Rag2-KO

Strain Name：C57BL/6JSmo-Rag2em2Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190429
Validation Data：Presence  |  Publications：2piece

Partial exon 3 of Rag2 gene was deleted to generate Rag2 knockout mice. Deletion of this region will cause frameshift and result in loss of function of mouse Rag2 gene.

Mice

Procr-CreERT2-2A-tdTomato

Strain Name：C57BL/6JSmo-Procrem5(CreERT2-P2A-tdtomato-Wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200227

A CreERT2-P2A-tdtomato-Wpre-pA expression cassette was knocked into the Procr gene start codon site.

Mice

Rag2/IL2rg-KO/hVEGFR2

Strain Name：C57BL/6JSmo-Il2rgem1Rag2em1Kdrtm2(hKDR)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220087

IL2rg-KO (NM-KO-210098) mice were crossed with Rag2-KO/hKDR (NM-HU-200280) mice to generate Rag2/IL2rg-KO/hKDR mouse models.

Mice

B2m-KO

Strain Name：C57BL/6JSmo-B2mem3Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18021
Validation Data：Presence  |  Publications：1piece

Exon2-3 of B2m gene were deleted to generate Ifngr1 knockout mice.

Mice

hCD40L

Strain Name：C57BL/6JSmo-Cd40lgtm1(hCD40L)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000033
Validation Data：Presence

The endogenous mouse Cd40lg gene was replaced by human CD40L gene.

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