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U-GEMMs

About 42,431 results
Mice

Wdfy1-CreERT2

Strain Name：C57BL/6Smoc-Wdfy1em(Kozak-CreERT2-WPRE-pA )Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-220121

Kozak-CreERT2-WPRE-pA expression cassette was knocked into the Wdfy1 gene start codon site.

Mice

hPD-1/hCD3E

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd3eem1(hCD3E)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18021

hPD-1（NM-HU-00015）was crossed with hCD3E（NM-HU-00114）to generate hPD-1/hCD3E。

Mice

hCD47(Balb/c,2)

Strain Name：BALB/cAnSmoc-Cd47em1(hCD47)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210359

The endogenous mice Cd47 gene was replaced by human CD47 gene. While hCD47(BALB/c)(Stock No.NM-HU-2000022) mice function similarly to hCD47(BALB/c,2) mice, for more detailed information please contact our technical advisor.

Mice

hCD3E(2)

Strain Name：C57BL/6Smoc-Cd3eem2(hCD3E)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210023

The endogenous mice Cd3e gene was replaced by human CD3E gene. While hCD3E(Stock No.NM-HU-00114) mice function similarly to hCD3E(2) mice,for more detailed information please contact our technical advisor.

Mice

hCXCR2

Strain Name：C57BL/6Smoc-Cxcr2em2(hCXCR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18025

The endogenous mouse Cxcr2 gene was replaced by human CXCR2 gene.

Mice

Braf-Flox-V600E

Strain Name：C57BL/6Smoc-Brafem1(flox-V600E)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190053

These mice carry a conditional p.V600E mutation of Braf gene.

Mice

R26-CAG-LSL-hHER2-IRES-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-HER2-luciferase-EGFP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190008

A SA-2xpolyA-CAG-LSL-HER2-IRES-Luciferase-2A-EGFP-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the HER2 protein.

Mice

A1Cf-KO

Strain Name：C57BL/6Smoc-A1Cfem1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 4 of A1Cf gene was deleted to generate A1Cf knockout mice.

Mice

hOX40/hCTLA-4

Strain Name：C57BL/6Smoc-Tnfrsf4em3(hTNFRSF4)Ctla4em1(hCTLA4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00105

These mice are OX40 and CTLA4 double knockin mouse models which can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hIL12RB2

Strain Name：C57BL/6Smoc-Il12rb2tm(hIL12RB2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215019

The endogenous mouse Il12rb2 gene was replaced by human IL12RB2 gene.

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