SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)Pdcd1em1(hPDCD1)Cd274em2(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220029
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Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd274em1(hCD274)Cd47em1(hCD47)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000095
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：BALB/cAnSmoc-Sirpatm(hSIRPA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210369
Research Application：inmmue therapy;drug screening
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Strain Name：BALB/cAnSmoc-Sirpatm4(hSIRPA)/SmocCd47em1(hCD47)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210020
Research Application：tumor research；inmmue therapy；drug screening
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Strain Name：C57BL/6Smoc-Slamf7em(hSLAMF7)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18028
Research Application：Immunotherapy,Cancer research,Drug screening
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Strain Name：C57BL/6Smoc-Tmem173tm2(hTMEM173)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190036
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：BALB/cAnSmoc-tmem173tm1(htmem173)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000049
Research Application：Immunotherapy,drug screening
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Strain Name：C57BL/6Smoc-Tigitem1(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00053
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Tigittm3(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200244
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Strain Name：BALB/cAnSmoc-Tigittm4(hTIGIT)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200245
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