SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Siglec15em1(hSIGLEC15)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190037
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：BALB/cAnSmoc-Siglec15em2(hSIGLEC15) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200001
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Sigleceem1(hSIGLEC8)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204983
Research Application：Immunotherapy, drug screening
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Strain Name：C57BL/6Smoc-Siglecfem1(hSIGLEC8)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210033
Research Application：inmmue therapy；drug screening
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Strain Name：C57BL/6Smoc-Sigleceem1(hSIGLEC9)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-225072
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Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18015
Research Application：Immunotherapy,drug screening
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Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000111
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)Ctla4em1(hCTLA4) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210368
Research Application：inmmue therapy;drug screening
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Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47) Pdcd1em1(hPDCD1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000090
Research Application：Immune-related
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Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210358
Research Application：inmmue therapy；drug screening
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