SMOC has developed a set of mouse models expressing humanized cytokines. These models are suitable to assess the efficacy of drugs targeting cytokines in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Il23aem3(hIL23A)Il12btm3(hIL12B)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-233778
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Strain Name：C57BL/6Smoc-Il3tm1(hIL3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190009
Research Application：Immune-related
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Strain Name：NOD-PrkdcscidIl2rgem1Il3em4(hIL3)/Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-007
Research Application：Immunotherapy,drug screening
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Strain Name：NOD-PrkdcscidIl2rgem1Tg(hIL3-hCSF2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215006
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Strain Name：C57BL/6Smoc-Il3tm3(hIL3)Csf2tm3(hCSF2)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190065
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：BALB/cAnSmoc-Il3tm(hIL3)Csf2tm(hCSF2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-230358
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Strain Name：C57BL/6Smoc-Il3tm1(hIL3)Csf2tm1(CSF2)Csf1tm2(CSF1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200271
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Strain Name：C57BL/6Smoc-Il31em2(IL31)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200008
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Il33tm2(hIL33)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000069
Research Application：Cytokine humanization model；drug screening
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