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U-GEMMs

Cytokines

SMOC has developed a set of mouse models expressing humanized cytokines. These models are suitable to assess the efficacy of drugs targeting cytokines in fully immunocompetent mice. 

Mice
hCSF3(NMG)
Strain Name：NOD-PrkdcscidIl2rgem1Gt(ROSA)26Sorem1(SA-LSL-hCSF3)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-232692
Mice
hCXCL13
Strain Name：C57BL/6Smoc-Cxcl13tm1(hCXCL13)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225079
Mice
hCXCL16
Strain Name：C57BL/6Smoc-Cxcl16em(hCXCL16)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215000
Mice
hGDF15
Strain Name：C57BL/6Smoc-Gdf15em(hGDF15)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-215002
Mice
hGITR(3)
Strain Name：C57BL/6Smoc-Tnfrsf18em1(hTNFRSF18)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-233216
Mice
hHGF
Strain Name：C57BL/6Smoc-Hgfem1(hHGF)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200235
Mice
hIFNA1
Strain Name：C57BL/6Smoc-Ifna1em(hIFNA1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220356
Mice
hIFNG
Strain Name：C57BL/6Smoc-Ifngtm(hIFNG)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220358
Mice
hIL-8-TG
Strain Name：C57BL/6Smoc-Tg(hIL-8)1Smoc
Strain State：Developing | Cat. NO.：NM-TG-225012
Mice
hIL10
Strain Name：C57BL/6Smoc-Il10tm4(hIL10)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000063
Research Application：Cytokine humanization model；drug screening
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