U-GEMMs

Cytokines

SMOC has developed a set of mouse models expressing humanized cytokines. These models are suitable to assess the efficacy of drugs targeting cytokines in fully immunocompetent mice. 

Mice
Strain Name:NOD.Cg-PrkdcscidIl2rgem1SmocIl15em1(hIL15)Smoc
Strain State:Repository Live | Cat. NO.:GM-NVG-210001
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:NOD-PrkdcscidIl2rg-Tg(pCMV-hIL34-pA)1Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-220433
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(pCAG-FRT-loxp-stop-loxp-hCD63-copGFP-6xHis-WPRE-polyA-FRT)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200044
Research Application:Exosome tracing model
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-Loxp-Stop-Loxp-Kozak-hIL2 signal peptide-hIL15-Flag-IRES-EGFP-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-220130
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