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Models

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Mice

Aak1-Flox

Strain Name：C57BL/6Smoc-Aak1em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253921

These mice carry loxP sites flanking exon 2 of Aak1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aak1 gene.

Mice

hLAIR1

Strain Name：C57BL/6JSmo-Lair1tm2(LAIR1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000011

The endogenous mouse Lair1 gene was replaced by human LAIR1 gene .

Mice

hIL2RA/hIL2RG

Strain Name：C57BL/6JSmo-Il2rgtm1(IL2RG)Il2ratm1(hIL2RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220144

hIL2RG(NM-HU-200007) mice were crossed with hIL2RA(NM-HU-190064) mice to generate hIL2RA/hIL2RG mice.

Mice

Notch3-R170C

Strain Name：C57BL/6JSmo-Notch3em1(R170C)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200254
Publications：1piece

These mice carry a p.R170C mutation of Notch3 gene.

Mice

Il1f6-Luc-2A-EGFP

Strain Name：C57BL/6JSmo-Il1f6em1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00017

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon.The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il1f6.

Mice

hLGALS9

Strain Name：C57BL/6JSmo-Lgals9tm(hLGALS9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215009
Validation Data：Presence

The endogenous mice Lgals9 gene was replaced by human LGALS9 gene.

Mice

Lmna-c.C1827T

Strain Name：C57BL/6JSmo-Lmnatm1(G609G)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200284
Validation Data：Presence

These mice carry a G609G mutation of Lmna gene.

Mice

Pdyn-IRES-Cre

Strain Name：C57BL/6JSmo-Pdynem1(IRES-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200089
Validation Data：Presence

A IRES-iCre expression cassette was knocked into the Pdyn gene stop codon site. Pdyn encodes prodynorphin. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying depression, stress, anxiety, pain response, circadian rhythm and appetite control.

Mice

Mnx1-IRES-Cre

Strain Name：C57BL/6JSmo-Mnx1em1(IRES-Cre-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200010
Validation Data：Presence

A IRES-Cre-WPRE-polyA expression cassette was knocked into the Mnx1 gene stop codon site. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Mnx1. These mice may be useful for studying spinal muscular atrophy (SMA).

Mice

Osr2-IRES-CreERT2

Strain Name：C57BL/6JSmo-Osr2em(IRES-CreERT2-Wpre-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215086

IRES-CreERT2-Wpre-pA expression cassette was knocked into the Osr2 gene .

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