Therapeutic Target-Humanized Mice
Cre/Dre-Driver Mice
Immunodeficient NMG Mice
Strain Name:C57BL/6JSmo-Sirpatm2(hSIRPA)Cd47tm1(hCD47) Pdcd1tm1(hPDCD1)Smoc Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-2000090
hPD-1(NM-HU-00015),hCD47(NM-HU-00050) were crossed with hSIRPA(2) (NM-HU-18015) to generate hSIRPA(2)/hCD47/hPD-1.
Strain Name:C57BL/6JSmo-Ucp1em2(Kozak-Cre-WPRE-pA)Smoc Strain State:Repository Live | Cat. NO.:NM-KI-190105 Validation Data:Presence
A Kozak-Cre-WPRE-pA expression cassette was knocked into the Ucp1 gene start codon site.
Strain Name:C57BL/6JSmo-Gt(ROSA)26Sortm(SA-polyA-CAG-LSL-TPM3-NTRK1-IRES-luc-2A-tdTomato-WPRE-polyA)Smoc Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-190098
These mice harbor a SA-polyA-CAG-LSL-TPM3-NTRK1-IRES-luc-2A-tdTomato-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.
Strain Name:C57BL/6JSmo-Il4tm3(hIL4)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190071 Validation Data:Presence
The endogenous mouse Il4 gene was completely or partially replaced by human IL4 gene via ESC targeting.
Strain Name:C57BL/6JSmo-Il7em1(Luc-eGFP)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00092
A Luciferase-2a-egfp-polyA cassette was inserted at ATG site of mouse Il7 gene.
Strain Name:C57BL/6JSmo-Slc32a1em1(IRES-iCre)Smoc Strain State:Repository Live | Cat. NO.:NM-KI-200081 Validation Data:Presence
A IRES-iCre expression cassette was knocked into the Slc32a1 gene stop codon site.
Strain Name:C57BL/6JSmo-Itgamtm1(IRES-hCD89-WPRE-polyA)Smoc Strain State:Repository Live | Cat. NO.:NM-KI-200063 Validation Data:Presence | Publications:1piece
A IRES-hCD89-WPRE-polyA expression cassette was knocked into the Itgam gene stop codon site.
Strain Name:C57BL/6JSmo-Slc34a1em1Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200642
Exon 3-6 of Slc34a1 gene was deleted to generate Slc34a1 knockout mice.
Strain Name:C57BL/6JSmo-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Tnfrsf9tm2(TNFRSF9)Smoc Strain State:Repository Live | Cat. NO.:NM-HU-220110
hCD3EDG(NM-HU-220120) mice were crossed with h4-1BB(2)(NM-HU-190077) to generate hCD3EDG/h4-1BB(2) mice.
Strain Name:C57BL/6JSmo-Pnpla3em1(I148M)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200185
These mice carry a I148M mutation of Pnpla3 gene.
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