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Models

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Mice

hTIGIT/hCCR8

Strain Name：C57BL/6JSmo-Tigittm1(hTIGIT)Ccr8tm1(hCCR8)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210426

hTIGIT(NM-HU-00053) was crossed with hCCR8(NM-HU-190053) to generate hTIGIT/hCCR8 mice.

Mice

hSIRPA(2)/hCD47/hCTLA-4

Strain Name：C57BL/6JSmo-Sirpatm2(hSIRPA)Cd47tm1(hCD47)Ctla4tm1(hCTLA4) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210368

hCTLA4(NM-HU-00014) was crossed with hSIRPA(2)/hCD47(NM-HU-2000111）to generate hSIRPA(2)/hCD47/hCTLA4 mice

Mice

Col3a1-2A-Cre

Strain Name：C57BL/6JSmo-Col3a1em(2A-Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220106

2A-Cre expression cassette was knocked into the Col3a1 gene stop codon site.

Mice

hIL5/hIL5R(3)

Strain Name：C57BL/6JSmo-Il5tm3(hIL5)Il5ratm3(hIL5RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220011
Validation Data：Presence

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(2)(Stock No.NM-HU-220010) function similarly to hIL5/hIL5R(3) mice, for more detailed information please contact our technical advisor.

Mice

Scx-IRES-CreERT2

Strain Name：C57BL/6JSmo-Scxem(IRES-CreERT2-Wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-215092
Validation Data：Presence

IRES-CreERT2-Wpre-pA expression cassette was knocked into the Scx gene .

Mice

hIGHA1

Strain Name：C57BL/6JSmo-sμtm1(hIGHA1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000086
Validation Data：Presence

The endogenous mouse sμ region was replaced by human IGHA1.

Mice

R26-CAG-LSL-hFGFR2*W290C-IRES-Luc-2A-EGFP

Strain Name：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-LSL-FGFR2(W290C)-IRES-Luciferase-2A-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190080

These mice harbor a CAG-LSL-FGFR2(W290C)-IRES-Luciferase-2A-EGFP cassette in the Rosa26 locus generated by homologous recombination.

Mice

Ccl4-c-Rox-TGATAA-Stop-c-Rox-2A-Cre

Strain Name：C57BL/6JSmo-Ccl4em(c-Rox-TGATAA-Stop-c-Rox-2A-Cre-Wpre-pA)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225056

c-Rox-TGATAA-Stop-c-Rox-2A-Cre-Wpre-pA expression cassette was knocked into the Ccl4 gene .

Mice

hNR3C1

Strain Name：C57BL/6JSmo-Nr3c1tm1(hNR3C1)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-225058

The endogenous mouse Nr3c1 gene was replaced by human NR3C1 gene.

Mice

hPD-1/hPD-L1/hLAG3

Strain Name：C57BL/6JSmo-Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Lag3tm1(hLAG3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190028

hPD-1(NM-HU-00015),hPD-L1(NM-HU-00062) were crossed with hLAG3(NM-HU-00049) to generate hPD-1/hPD-L1/hLAG3.

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