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Models

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Mice

Nmu-2A-Cre

Strain Name：C57BL/6JSmo-Nmuem1(2A-Cre-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200298
Validation Data：Presence

2A-Cre-WPRE-polyA expression cassette was knocked into the Nmu gene stop codon site. Nmu gene encodes a member of the neuromedin family of neuropeptides. The encoded protein plays a role in energy homeostasis and body temperature regulation. And the protein is homologous with human NMU, which is linked toobesity.

Mice

hIL4/hIL4R

Strain Name：C57BL/6JSmo-Il4tm3(hIL4)Il4ratm1(hIL4R)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000106
Validation Data：Presence

These mice are obtained through breeding of two single gene humanized mice.

Mice

hIL7(BALB/c)

Strain Name：BALB/cJSmo-Il7tm1(hIL7)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220014
Validation Data：Presence

The endogenous mouse Il7r gene was replaced by human IL7R gene.

Mice

Myf5-Cre

Strain Name：C57BL/6JSmo-Myf5em1(Cre-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200147
Validation Data：Presence

A Cre-WPRE-polyA expression cassette was knocked into the Myf5 gene start codon site. Myogenic factor 5 (Myf5) belongs to the MRF family transcription factors that regulate myogenesis. It is expressed in the skeletal muscle and satellite cells. Severe loss of skeletal muscle following ablation of Myf5-expressing progenitors. This strain is useful in studying the differentiation of skeletal muscle.

Mice

Etv1-CreERT2

Strain Name：C57BL/6JSmo-Etv1em1(CreERT2-SV40-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200105
Validation Data：Presence

A CreERT2 expression cassette was knocked into the Etv1 gene start codon site. ETV1 expression is enriched in fast conduction tissues of embryonic and adult mammalian hearts. And ETV1 expression is upregulated in the atrial tissue of patients with permanent atrial fibrillation. Etv-CreERT2 mice can be applied to heart disease research. ETV1 is also expressed in retinal ganglion cells of adult mice, and the mouse model can be used to study how retinal ganglion cells contribute to visual processing in the brain.

Mice

Foxj1-EGFP-CreERT2

Strain Name：C57BL/6JSmo-Foxj1em1(GFP-CreERT2-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200133
Validation Data：Presence

A GFP-CreERT2-polyA expression cassette was knocked into the Foxj1 gene start codon site.

Mice

Il11-Luc-2A-EGFP

Strain Name：C57BL/6JSmo-Il11em1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00036

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il11.

Mice

hTNFa-Tg

Strain Name：C57BL/6JSmo-Tgtn(hTNFa promoter-hTNFa-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-200004
Validation Data：Presence

These transgenic mice harbor hTNFa promoter-hTNFa-pA expression cassette.

Mice

Il7r-Cre

Strain Name：C57BL/6JSmo-Il7rem1(Cre-Wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200306
Validation Data：Presence

Cre-Wpre-pA expression cassette was knocked into the Il7r gene start codon site.

Mice

Cela1-2A-DreERT2

Strain Name：C57BL/6JSmo-Cela1em1(2A-DreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190094
Validation Data：Presence  |  Publications：1piece

A 2A-DreERT2 expression cassette was knocked into the Cela1 gene stop codon site.

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