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Models

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Mice

hIL2RG/hIL2RB

Strain Name：C57BL/6JSmo-Il2rgtm1(IL2RG)Il2rbtm1(hIL2RB)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210354
Validation Data：Presence

hIL2RG(NM-HU-200007) was crossed with hIL2RB(NM-HU-2000055) to generate hIL2RG/hIL2RB mice.

Mice

Piezo1-CreERT2

Strain Name：C57BL/6JSmo-Piezo1tm2(CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18048

This tamoxifen-inducing Piezo1-CreERT2 tool mouse model was established by inserting a 2A-CreERT2 co-expression cassette into the Piezo1 gene stop codon site .

Mice

R26-SA-LSL-DTR-IRES-tdTomato

Strain Name：C57BL/6JSmo-Gt(ROSA)26Sorem1(SA-LSL-DTR-IRES-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210136

A SA-LSL-DTR-IRES-tdTomato expression cassette was knocked into via the Rosa26 locus.

Mice

Calb1-2A-GFPCre

Strain Name：C57BL/6JSmo-Calb1em1(2A-EGFP-Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200141
Validation Data：Presence

A 2A-EGFP-Cre expression cassette was knocked into the Calb1 gene stop codon site. Calb1 is highly expressed in the brain. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. This strain is useful in studying many neurobehavioral diseases such as spatial learning and circadian rhythm interference. It has been reported that the incidence of many diseases may be different between genders.

Mice

hCD3EDG/hCD28

Strain Name：C57BL/6JSmo-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd28tm2(hCD28)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220113
Validation Data：Presence

hCD3EDG(NM-HU-220120) mice were crossed with hCD28(NM-HU-190011) to generate hCD3EDG/hCD28 mouse

Mice

Wdfy1-CreERT2

Strain Name：C57BL/6JSmo-Wdfy1em(Kozak-CreERT2-WPRE-pA )Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220121

Kozak-CreERT2-WPRE-pA expression cassette was knocked into the Wdfy1 gene start codon site.

Mice

Foxp3-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6JSmo-Foxp3em1(IRES-Luci-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200065

A IRES-luci-2A-tdTomato expression cassette was knocked into the Foxp3 gene stop codon site.

Mice

Ncr1-IRES-Cre

Strain Name：C57BL/6JSmo-Ncr1em(IRES-Cre)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225008
Validation Data：Presence

IRES-Cre expression cassette was knocked into the Ncr1 gene .

Mice

hDLL4

Strain Name：C57BL/6JSmo-Dll4tm1(hDLL4)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000020
Validation Data：Presence

The endogenous mouse Dll4 gene was replaced by human DLL4 gene.

Mice

Trp63-CreERT2

Strain Name：C57BL/6JSmo-Trp63em(CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225021
Validation Data：Presence

A CreERT2-Wpre-polyA expression cassette was knocked into the exon4 of Trp63 gene via CRISPR/Cas mediated recombination.

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