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Models

About 43,835 results
Mice

Nphs2-CreERT2

Strain Name：C57BL/6JSmo-Nphs2tm1(IRES-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00128
Validation Data：Presence

An IRES-CreERT2 co-expression cassette is inserted into 3'UTR region of Nphs2 gene via homologous recombination to establish a tamoxifen inducible Nphs2-CreERT2 tool stain.

Mice

hIL18

Strain Name：C57BL/6JSmo-Il18tm1(hIL18)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210038
Validation Data：Presence

The endogenous mice Il18 gene was replaced by human IL18 gene.

Mice

Tagln-2A-DreERT2

Strain Name：C57BL/6JSmo-Taglnem1(2A-DreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215038
Validation Data：Presence

2A-DreERT2 expression cassette was knocked into the Tagln gene. Tagln-2A-DreERT2(2) (Stock No.NM-KI-215094) is similar to this strain.

Mice

hAPOE3

Strain Name：C57BL/6JSmo-Apoetm3(hAPOE3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190003
Validation Data：Presence

This APOE3 humanized mouse model was established by replacing the mouse Apoe gene coding exons and introns with the human APOE3 corresponding sequence by homologous recombination.

Mice

Txlna-Luc-EGFP

Strain Name：C57BL/6JSmo-Txlnaem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00026

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Txlna.

Mice

hMAPT

Strain Name：C57BL/6JSmo-Mapttm1(hMAPT)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200116
Validation Data：Presence

The endogenous mouse Mapt gene was replaced by human MAPT gene.

Mice

Pax7-2A-DreERT2

Strain Name：C57BL/6JSmo-Pax7em1(2A-DreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190124
Validation Data：Presence  |  Publications：1piece

A 2A-DreERT2 expression cassette was knocked into the Pax7 gene stop codon site.

Mice

hIL9(BALB/c)

Strain Name：BALB/cJSmo-Il9tm3(hIL9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220012
Validation Data：Presence

The endogenous mouse Il9 gene was replaced by human IL9 gene.

Mice

Xcr1-IRES-Cre

Strain Name：C57BL/6JSmo-Xcr1em1(IRES-iCre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200237
Validation Data：Presence

A IRES-iCre expression cassette was knocked into the Xcr1 gene stop codon site.

Mice

hCD47/hSIRPA(2)

Strain Name：C57BL/6JSmo-Sirpatm2(hSIRPA)Cd47tm1(hCD47)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000111
Validation Data：Presence

This SIRPA and CD47 double Knock-in strain is established by crossing hSIRPA and hCD47 mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.While hSIRPA/hCD47 (Stock No.NM-HU-190019) have been pulled from shelves for some reasons.

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