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Models

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Mice

hICOS

Strain Name：C57BL/6JSmo-Icostm1(hICOS)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00052
Validation Data：Presence

The endogenous mouse Icos gene was replaced by human ICOS gene. While hICOS(2)(Stock No.NM-HU-190030) mice function similarly to hICOS mice,for more detailed information please contact our technical advisor.

Mice

Itgax-2A-DreERT2

Strain Name：C57BL/6JSmo-Itgaxem1(2A-DreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190032
Publications：1piece

A 2A-DreERT2 expression cassette was knocked into the Itgax gene stop codon site.

Mice

Fah-KO

Strain Name：C57BL/6JSmo-Fahem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-191202

Partial exon 8 of Fah gene was deleted to generate Fah knockout mice.

Mice

hDMPK

Strain Name：C57BL/6JSmo-Dmpktm1(hDMPK)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225084
Validation Data：Presence

The endogenous mouse Dmpk gene was replaced by human DMPK gene.

Mice

hIL6ST

Strain Name：C57BL/6JSmo-Il6sttm1(hIL6ST)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204980

The endogenous mice Il6st gene was replaced by human IL6ST gene.

Mice

hCD40/hPD-1/hPD-L1

Strain Name：C57BL/6JSmo-Cd40tm1(hCD40)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210406

hPD-1/hPD-L1(NM-HU-00100) was crossed with hCD40（NM-HU-00076）to generate hCD40/hPD-1/hPD-L1 mice

Mice

Pvalb-2A-mCherry

Strain Name：C57BL/6JSmo-Pvalbem(2A-mCherry)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220177

2A-mCherry expression cassette was knocked into the Pvalb gene stop codon site.

Mice

Pax8-Cre

Strain Name：C57BL/6JSmo-Pax8em1(Cre-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200151
Validation Data：Presence

A Cre-WPRE-polyA expression cassette was knocked into the Pax8 gene start codon site.

Mice

Sox9-IRES-CreERT2

Strain Name：C57BL/6JSmo-Sox9em(IRES-CreERT2-SV40pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-204996
Validation Data：Presence  |  Publications：1piece

IRES-CreERT2-SV40pA expression cassette was knocked into the Sox9 gene .

Mice

hPD-L1/hCTLA-4

Strain Name：C57BL/6JSmo-Ctla4tm1(hCTLA4)Cd274tm1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00102
Validation Data：Presence

hPD-L1(NM-HU-00062) was crossed with hCTLA4(NM-HU-00014)to generate hPD-1/hCTLA4 mice

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