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Models

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mouse

Chrnb2-KO

Strain Name:C57BL/6JSmo-Chrnb2em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-2105377

Exon 2 of Chrnb2 gene was deleted to generate Chrnb2 knockout mice.

mouse

R26-CAG-LSL-hEGFR*T790M-IRES-Luc-2A-tdTomato

Strain Name:C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-LSL-EGFR (T790M) -IRES-Luciferase-2A-tdTomato)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-190070

These mice harbor a CAG-LSL-EGFR(T790M)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

mouse

Aard-Flox

Strain Name:C57BL/6JSmo-Aardem1(flox)Smoc
Strain State:Developing | Cat. NO.:NM-CKO-260844

These mice carry loxP sites flanking exon1-2 of Aard gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aard gene.

mouse

hPD-1/hSIRPA(2)

Strain Name:C57BL/6JSmo-Pdcd1tm1(hPDCD1)Sirpatm2(hSIRPA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000089

hPD-1(NM-HU-00015) was crossed with hSIRPA(2) (NM-HU-18015) to generate hPD-1/hSIRPA(2).

mouse

Tmem119-2A-tdTomato

Strain Name:C57BL/6JSmo-Tmem119em3(P2A-tdTomato)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200236
Validation Data:Presence

A P2A-tdTomato expression cassette was knocked into the Tmem119 gene stop codon site.

mouse

hLAIR1

Strain Name:C57BL/6JSmo-Lair1tm2(LAIR1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000011

The endogenous mouse Lair1 gene was replaced by human LAIR1 gene .

mouse

hIL2RA/hIL2RG

Strain Name:C57BL/6JSmo-Il2rgtm1(IL2RG)Il2ratm1(hIL2RA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220144

hIL2RG(NM-HU-200007) mice were crossed with hIL2RA(NM-HU-190064) mice to generate hIL2RA/hIL2RG mice.

mouse

Notch3-R170C

Strain Name:C57BL/6JSmo-Notch3em1(R170C)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200254
Publications:1piece

These mice carry a p.R170C mutation of Notch3 gene.

mouse

Tyk2-KO

Strain Name:C57BL/6JSmo-Tyk2em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-201976

Exon 4 of Tyk2 gene was deleted to generate Tyk2 knockout mice.

mouse

Il1f6-Luc-2A-EGFP

Strain Name:C57BL/6JSmo-Il1f6em1(Luc-eGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00017

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon.The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il1f6.

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