Welcome to Advanced Search

Models

About 43,894 results
mouse

Dmp1-KO

Strain Name：C57BL/6JSmo-Dmp1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200634

Exon 4-6 of Dmp1 gene was deleted to generate Dmp1 knockout mice.

mouse

R26-pVillin1-hCYP3A4-IRES-tdTomato(FVB)

Strain Name：FVB-Gt(ROSA)26Sortm1(Gut-CYP3A4-IRES-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18033

Intestinal expression of the CYP3A enzyme in the human body can cause significant intestinal metabolism of the compound, resulting in impaired drug absorption. This knock-in model was generated by inserting the human CYP3A4 cDNA driven by the Villin1 promoter together with the IRES-tdTomato reporter gene into mosue Rosa26 site, which can be crossed with the Cyp3a13 gene knockout and other Cyp3a family genes knockout mice to obtain intestinal-expressed CYP3A4 humanized mouse model in order to determine the contribution of intestinal metabolism to the absorption and distribution of test article.

mouse

Opn4-Cre

Strain Name：C57BL/6JSmo-Opn4em1(Cre-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200304
Validation Data：Presence

Cre-WPRE-polyA expression cassette was knocked into the Opn4 gene start codon site. The melanopsin gene (Opn4) encodes a functional photopigment. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying circadian rhythm regulation.

mouse

Ptger3-2A-Cre

Strain Name：C57BL/6JSmo-Ptger3em(2A-Cre)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225027

2A-Cre expression cassette was knocked into the Ptger3 gene .

mouse

hIL4/hIL4R(BALB/c)

Strain Name：BALB/cJSmo-Il4tm3(hIL4)Il4ratm1(hIL4RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220167
Validation Data：Presence

The endogenous mouse Il4,Il4ra gene was replaced by human IL4 gene.

mouse

hLY96

Strain Name：C57BL/6JSmo-Ly96tm1(hLY96)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210003
Validation Data：Presence

The endogenous mice Ly96 gene was replaced by human LY96 gene

mouse

Rag1-KO

Strain Name：C57BL/6JSmo-Rag1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-252600

The exon 2 of Rag1 gene was deleted to generate Rag1 knockout mouse.

mouse

Aacs-KO

Strain Name：C57BL/6JSmo-Aacsem1Smoc
Strain State：Developing | Cat. NO.：NM-KO-261269

The exon 2 of Aacs gene was deleted to generate Aacs knockout mouse.

mouse

R26-CAG-LSL-hFGFR2*K659N-IRES-Luc-2A-EGFP

Strain Name：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-LSL-FGFR2(K659N)-IRES-Luciferase-2A-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190078

These mice harbor a CAG-LSL-FGFR2(K659N)-IRES-Luciferase-2A-EGFP cassette in the Rosa26 locus generated by homologous recombination.

mouse

hCD47/hPD-1/hPD-L1/hSIRPA(2)

Strain Name：C57BL/6JSmo-Sirpatm2(hSIRPA)Cd47tm1(hCD47)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210358

hSIRPA(2)(NM-HU-18015)，hCD47(NM-HU-00050), hPD-1(NM-HU-00015), hPD-L1(NM-HU-00062)was crossed together to generate hSIRPA(2)/hCD47/hPD-1/hPD-L1 mice.

Email Back to top