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Models

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mouse

hIL5/hIL5R(2)

Strain Name：C57BL/6JSmo-Il5tm3(hIL5)Il5ratm2(hIL5RA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-220010
Validation Data：Presence

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(3)(Stock No.NM-HU-220011) function similarly to hIL5/hIL5R(2) mice, for more detailed information please contact our technical advisor.

mouse

R26-CAG-LSL-hTARDBP*A315T-EGFP

Strain Name：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-LSL-3xFlag-TARDBP(A315T)-IRES-GFP-WPRE-PA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200019

These mice harbor a CAG-LSL-3xFlag-TARDBP(A315T)-IRES-GFP-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination.

mouse

R26-CAG-2xKRAB-dCas9-IRES-EGFP

Strain Name：C57BL/6JSmo-Gt(ROSA)26Sorem1(CAG-Loxp-2xKRAB-dCas9-IRES-EGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18007
Validation Data：Presence

These mice harbor a CAG-LSL-2xKRAB-dCas9-IRES-EGFP-WPRE-pA conditional expression cassette in mouse Rosa26 loci via homologous recombination. This strain can be used in CRISPR mediated target gene transcriptional inhibition (CRISPRi). The loxp-stop-loxp cassette was deleted.

mouse

ICR

Strain Name：ICR
Strain State：Repository Live | Cat. NO.：SM-006
Validation Data：Presence

ICR

mouse

hCD47/hCTLA-4/hSIRPA(2)

Strain Name：C57BL/6JSmo-Sirpatm2(hSIRPA)Cd47tm1(hCD47)Ctla4tm1(hCTLA4) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210368

The hCD47/hSIRPA(2) (NM-HU-2000111) was crossed with hCTLA-4(NM-HU-00014) to generate hCD47/hSIRPA(2)/hCTLA-4 mice.

mouse

Tmem119-IRES-Cre

Strain Name：C57BL/6JSmo-Tmem119em1(IRES-Cre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-225007
Validation Data：Presence

IRES-Cre expression cassette was knocked into the Tmem119 gene stop codon site.

mouse

1300017j02Rik-KO

Strain Name：C57BL/6JSmo-1300017j02Rikem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190231

This 1300017j02Rik knockout mouse model was generated by knocking out the exon2-12 region of the 1300017j02Rik.

mouse

hIL17RA(BALB/c)

Strain Name：BALB/cJSmo-Il17ratm1(hIL17RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220015
Validation Data：Presence

The endogenous mouse Il17ra gene was replaced by human IL17RA gene.

mouse

Ace2-KO

Strain Name：C57BL/6JSmo-Ace2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190906

exon 3-7 of Ace2 gene was deleted to generate Ace2 knockout mice.

mouse

Mesp1-CreERT2

Strain Name：C57BL/6JSmo-Mesp1em(CreERT2-Wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-215087

CreERT2-Wpre-pA expression cassette was knocked into the Mesp1 gene .

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