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Models

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mouse

Ywhaz-KO

Strain Name：C57BL/6JSmo-Ywhazem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-202154

Exon 4 of Ywhaz gene was deleted to generate Ywhaz knockout mice.

mouse

Nkx3-1-IRES-CreERT2

Strain Name：C57BL/6JSmo-Nkx3-1em1(IRES-CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200071
Validation Data：Presence

A IRES-CreERT2 expression cassette was knocked into the Nkx3-1 gene stop codon site.

mouse

hPD-1/hIL1B

Strain Name：C57BL/6JSmo-Pdcd1tm1(hPDCD1)Il1btm3(hIL1B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210018

hPD-1(NM-HU-00015) was crossed with hIL1B(NM-HU-190047) to generate hPD-1/hIL1B mice

mouse

Itgam-IRES-DTRGFP

Strain Name：C57BL/6JSmo-Itgamem1(IRES-DTR-EGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200066
Validation Data：Presence

A IRES-DTR-EGFP expression cassette was knocked into the Itgam gene stop codon site.

mouse

IL1B-Luc-Tg

Strain Name：B6.Cg-Tg(IL1B-Luc)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-TG-00001
Validation Data：Presence  |  Publications：1piece

The transgenic mice model could be used to study transcriptional regulation of the IL-1βgene expression in the inflammatory process and evaluation the effect of anti-inflammatory drug in vivo.

mouse

hIL13/hOX40

Strain Name：C57BL/6JSmo-Il13tm2(hIL13)Tnfrsf4tm1(hTNFRSF4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220024

hIL13(NM-HU-190069) was crossed with hOX40(NM-HU-00041) to generate hIL13/hOX40 mice.

mouse

Stat3-Flox

Strain Name：C57BL/6JSmo-Stat3tm7(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200050

These mice carry loxP sites flanking exon 12-14 of Stat3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Stat3 gene.While Stat3-Flox(in-frame mutation)(Stock No.NM-CKO-200225）mice carrying the loxP sites flanking exon 18-20 of Stat3 gene.

mouse

Aak1-KO

Strain Name：C57BL/6JSmo-Aak1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200002

Exon 3 of Aak1 gene was deleted to generate Aak1 knockout mice.

mouse

R26-CAG-LSL-hIDH2*R140Q-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-LSL-IDH2(R140Q)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190075

These mice harbor a CAG-LSL-IDH2(R140Q)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

mouse

A3galt2-Flox

Strain Name：C57BL/6JSmo-A3galt2em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253844

These mice carry loxP sites flanking exon 2-4 of A3galt2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A3galt2 gene.

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