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mouse

hNR1I3

Strain Name：C57BL/6JSmo-Nr1i3tm2(hNR1I3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200253
Validation Data：Presence

The endogenous mice Nr1i3 gene was replaced by human NR1I3 gene.

mouse

Cdkal1-Flox

Strain Name：C57BL/6JSmo-Cdkal1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-234794

These strains carry loxP sites flanking exon 5 of Cdkal1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Cdkal1 gene.

mouse

Ifng-Venus-Luc

Strain Name：C57BL/6JSmo-Ifngem1(IRES-Venus-Luci)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18041
Validation Data：Presence

An IRES-Venus-Luci co-expression cassette was inserted in 3'UTR region of Ifng gene.

mouse

hCD3EDG/hCD40

Strain Name：C57BL/6JSmo-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd40tm1(hCD40)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220116

hCD3EDG(NM-HU-220120) mice were crossed with hCD40(NM-HU-00076) to generate hCD3EDG//hCD40 mice.

mouse

hPD-1/hPD-L1/hCD73(2)

Strain Name：C57BL/6JSmo-Pdcd1tm1(hPD-1)Cd274tm1(hPD-L1)Nt5etm2(hNT5E)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210410

hPD-1(NM-HU-00015) was crossed with hPD-L1/hCD73(2)(NM-HU-210356) to generate hPD-1/hPD-L1/hCD73(2) mice.

mouse

MHC Class II (I-A/I-E) -KO

Strain Name：C57BL/6JSmo-H2-Ab1em1H2-Aaem1 H2-Eb1em1H2-Eb2em1H2-Ea-ps em1 Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18032
Validation Data：Presence

All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models. These MHC class II molecule-deficient mice were on the C57BL/6J genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins.

mouse

hKLRK1

Strain Name：C57BL/6JSmo-Klrk1tm1(hKLRK1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190005
Validation Data：Presence

The endogenous mouse Klrk1 gene was replaced by human KLRK1 gene.

mouse

hNR1I2

Strain Name：C57BL/6JSmo-Nr1i2tm3(hNR1I2)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000066
Validation Data：Presence

The endogenous mouse Nr1i2 gene was replaced by human NR1I2 gene.

mouse

Slc6a3-KO

Strain Name：C57BL/6JSmo-Slc6A3em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-191034

Exon 4 of Slc6a3 gene was deleted to generate Slc6a3 knockout mice.

mouse

Col4a5-R471X

Strain Name：C57BL/6JSmo-Col4a5em1(R471X)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200183
Validation Data：Presence

These mice carry a R471X mutation of Col4a5 gene.

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