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Models

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mouse

hIL17RB(2)

Strain Name：C57BL/6JSmo-Il17rbtm2(hIL17RB)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200225

The endogenous mice Il17rb gene was replaced by human IL17RB gene. While hIL17RB(Stock No.NM-HU-200224) mice function similarly to hIL17RB(2) mice,for more detailed information please contact our technical advisor.

mouse

hLYPD3

Strain Name：C57BL/6JSmo-Lypd3tm1(hLYPD3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200248

The endogenous mice Lypd3 gene was replaced by human LYPD3 gene.

mouse

A4gnt-KO

Strain Name：C57BL/6JSmo-A4gntem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-201369

Exon 2-3 of A4gnt gene was deleted to generate A4gnt knockout mice.

mouse

A4galt-KO

Strain Name：C57BL/6JSmo-A4galtem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200001

Exon 3 of A4galt gene was deleted to generate A4galt knockout mice.

mouse

Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1/hCTLA-4

Strain Name：C57BL/6JSmo-Fcgr2bem1Fcgr3em1Fcgr4em1Pdcd1em1(hPDCD1)Ctla4em1(hCTLA4)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-220070

The Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1/hCTLA4 mouse model was obtained by deleting sequences from upstream of Fcgr3 gene to the 3'UTR of Fcgr2b gene in the hPD-1/hCTLA4(NM-HU-00079) mouse.

mouse

hICOSL(2)

Strain Name：C57BL/6JSmo-Icosltm3(hICOSLG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000068
Validation Data：Presence

The endogenous mouse Icosl gene was replaced by human ICOSLG gene. While hICOSL(Stock No.NM-HU-00095) mice function similarly to hICOSL(2) mice,for more detailed information please contact our technical advisor.

mouse

Lrp1-Flox

Strain Name：C57BL/6JSmo-Lrp1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-2101319

These mice carry loxP sites flanking exon 7-8 of Lrp1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Lrp1 gene.

mouse

hCTLA-4(2)

Strain Name：C57BL/6JSmo-Ctla4tm2(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190038

Extracellular domain of mouse Ctla4 gene was replaced by human CTLA4 gene. While hCTLA4(Stock No.NM-HU-00014) mice function similarly to hCTLA4(2) mice,for more detailed information please contact our technical advisor.

mouse

C1qa-KO

Strain Name：C57BL/6JSmo-C1qaemSmoc
Strain State：Repository Live | Cat. NO.：NM-KO-210110

exon 3 of C1qa gene was deleted to generate C1qa knockout mice.

mouse

Pax7-IRES-CreERT2

Strain Name：C57BL/6JSmo-Pax7em1(IRES-Cre-ERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200099
Validation Data：Presence

A IRES-Cre-ERT2 expression cassette was knocked into the Pax7 gene stop codon site. Pax7 is expressed in myogenic progenitor cells. Pax7 is essential for the myogenic potential, survival, and proliferation of myogenic progenitors. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Pax7 after tamoxifen treatment.

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