Strain Name：C57BL/6Smoc-Ntrk2em1(CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200146
A CreERT2-WPRE-polyA expression cassette was knocked into the Ntrk2 gene start codon site.
Ntrk2 encodes the tropomyosin receptor kinase B (TrkB), transmission through which neurotrophic factors modify differentiation, plasticity, and synaptic transmission. When these Ntrk2-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Ntrk2 expressing cells.
