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Models

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Mice

R26-CAG-LNL-ddCas9

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LNL-ddCas9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00063

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven ddCas9. The targeted mutation was inserted into the Gt(ROSA)26Sor locus.

Mice

Tcf7-2A-EGFP-2A-CreERT

Strain Name：C57BL/6Smoc-Tcf7em1(T2A-EGFP-P2A-CreERT)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-232120
Validation Data：Presence

The T2A-EGFP-P2A-CreERT expression cassette was knocked into the Tcf7 gene stop codon site.

Mice

R26-CAG-Cas9

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-Cas9)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00120
Validation Data：Presence

These mice were established by crossing R26-(CAG-LSL-Cas9) and EIIA mice together.

Mice

Gad2-2A-CreERT2

Strain Name：C57BL/6Smoc-Gad2em(2A-CreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-220291
Publications：1piece

2A-CreERT2 expression cassette was knocked into the Gad2 gene stop codon site.

Mice

Flt3-2A-DreERT2

Strain Name：C57BL/6Smoc-Flt3em2(2A-DreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190115
Validation Data：Presence  |  Publications：1piece

A 2A-DreERT2 expression cassette was knocked into the Flt3 gene stop codon site.

Mice

Cx3cr1-Cre

Strain Name：C57BL/6Smoc-Cx3cr1em1(iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200079
Validation Data：Presence

The coding region of Cx3cr1 gene was replaced by a iCre expression cassette via CRISPR/Cas9 mediated recombination.

Mice

H11-CAG-LSL-LSL-hMYCN-IRES-EGFP

Strain Name：C57BL/6Smoc-Igs2tm1(CAG-loxp-Neo-Stop-loxp-lox2272-Neo-Stop-lox2272-HA tag-NMYC-IRES-EFGP-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-210145

A CAG-loxp-Neo-Stop-loxp-lox2272-Neo-Stop-lox2272-HA tag-NMYC-IRES-EFGP-WPRE-polyA expression cassette was knocked into via the lgs2 (H11) locus.

Mice

R26-LSL-SmoM2W539L-IRES-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-loxp-stop-loxp-SmoM2(W539L)-IRES-tdTomato-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200035

These mice harbor a SA-loxp-stop-loxp-SmoM2(W539L)-IRES-tdTomato-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. W539L point mutation of the mouse gene (SmoM2), which corresponds to the W535L mutation in the human sequence.

Mice

hIL3-hCSF2-Tg(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1Tg(hIL3-hCSF2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-215006
Validation Data：Presence

These transgenic mice carry humanized IL3 and humanized CSF2.

Mice

Il2-IRES-Venus-Luc

Strain Name：C57BL/6Smoc-Il2em1(Venus-Luci)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18057
Validation Data：Presence

an IRES-Venus Luci cassette was inserted into the IL2 gene stop codon site.

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