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Models

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Mice

Thy1-CreERT2

Strain Name:C57BL/6Smoc-Thy1em1(Kozak-CreERT2-WPRE-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-231054
Validation Data:Presence

The Kozak-CreERT2-WPRE-pA expression cassette was knocked into the Thy1 gene start codon site.

Mice

Egr2-Cre

Strain Name:C57BL/6Smoc-Egr2em1(iCre-Wpre-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200132

A iCre-Wpre-pA expression cassette was knocked into the Egr2 gene start codon site.

Mice

hAPP

Strain Name:C57BL/6Smoc-Apptm(hAPP)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-220224

The endogenous mouse APP gene was replaced by human APP gene.

Mice

Cd34-LSL-DreERT2

Strain Name:C57BL/6Smoc-Cd34tm1(loxP-STOP-loxP-Kozak-DreERT2-WPRE-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-231444

The loxP-STOP-loxP-Kozak-DreERT2-WPRE-pA expression cassette was knocked into the Cd34 gene start codon site.

Mice

R26-CAG-LSL-Cas9-IRES-Luc

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-Cas9-IRES-Luciferase-pA)
Strain State:Repository Live | Cat. NO.:NM-KI-18002

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Cas9 gene followed by IRES-Luciferase coexpression cassette. The targeted mutation was inserted into the Rosa26 locus by homologous recombination.

Mice

Pdyn-IRES-Cre

Strain Name:C57BL/6Smoc-Pdynem1(IRES-iCre)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200089
Validation Data:Presence

A IRES-iCre expression cassette was knocked into the Pdyn gene stop codon site. Pdyn encodes prodynorphin. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying depression, stress, anxiety, pain response, circadian rhythm and appetite control.

Mice

R26-CAG-LSL-hCD2*C truncated

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LSL-hCD2 C truncated-WPRE-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200321

A CAG-LSL-hCD2 C truncated-WPRE-polyA expression cassette was knocked into the R26 locus.

Mice

Il23a-Luc-2A-EGFP

Strain Name:C57BL/6Smoc-Il23aem1(Luc-EGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00057

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il23a.

Mice

Syn1-IRES-CreERT2

Strain Name:C57BL/6Smoc-Syn1em1(IRES-CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-231789
Validation Data:Presence

The IRES-CreERT2 expression cassette was knocked into the Syn1 gene stop codon site.

Mice

Karma-2A-tdTomato-2A-DTR

Strain Name:C57BL/6Smoc-Gpr141bem1(2A-tdTomato-2A-DTR)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-210116

2A-tdTomato-2A-DTR expression cassette was knocked into the Karma gene.

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