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Models

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Mice

R26-CAG-LSL-hFGFR2-IRES-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-FGFR2-luciferase-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190007

A SA-2xpolyA-CAG-LSL-FGFR2-IRES-luciferase-2A-EGFP-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the FGFR2 protein.

Mice

R26-CAG-LSL-hNFE2L2*G81S-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-NFE2L2(G81S)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190077

These mice harbor a CAG-LSL-NFE2L2(G81S)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

Mice

KPC(2)

Strain Name：C57BL/6Smoc-Trp53tm7(R270H-flox)Krasem4(LSL-G12D)Tg(Pdx1-cre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-220014

Trp53-LSL-R270H, Kras-LSL-G12D were crossed with Pdx1-Cre-Tg to generate KPC mice. While KPC mice function similarly to KPC(2) mice, for more detailed information please contact our technical advisor.

Mice

Il23a-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il23aem1(Luc-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00057

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il23a.

Mice

Pgr-IRES-Cre

Strain Name：C57BL/6Smoc-Pgrem1(IRES-Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200150

A IRES-Cre expression cassette was knocked into the Pgr gene stop codon site.

Mice

Il5-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il5em1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00022

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il5.

Mice

Prox1-IRES-CreERT2

Strain Name：C57BL/6Smoc-Prox1em1(IRES-CreERT2-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200119

A IRES-CreERT2-pA expression cassette was knocked into the Prox1 gene stop codon site. Prox1 encodes a transcription factor (prospero-related homeobox 1) that is necessary for the formation and maintenance of lymphatic vessels. When Prox1-IRES-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible Cre-mediated recombination will result in deletion of the floxed sequences in PROX1positive cells.

Mice

R26-CAG-EGFP(3)

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem2(CAG-EGFP-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190090

These mice harbor a CAG-EGFP-WPRE-polyA cassette in the Rosa26 locus.2 generated by homologous recombination. While R26-CAG-EGFP(Stock No.NM-KI-190088) and R26-CAG-EGFP(2)(Stock No.NM-KI-190089) function similarly to R26-CAG-EGFP(3) mice,for more detailed information please contact our technical advisor.

Mice

R26-CAG-LSL-hEML4/ALK-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-emL4-ALK-IRES-Luciferase-2A-tdTomato)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190072

These mice harbor a CAG-LSL-EML4-ALK-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.Please check if the EML4-ALK fusion variant is what you need before ordering.

Mice

R26-CAG-LSL-hTARDBP*A315T-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-3xFlag-TARDBP(A315T)-IRES-GFP-WPRE-PA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200019

These mice harbor a CAG-LSL-3xFlag-TARDBP(A315T)-IRES-GFP-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination.

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