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Mice

Tie1-2A-Cre

Strain Name：C57BL/6Smoc-Tie1em1(2A-Cre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18023

A 2A-Cre coexpression cassette is inserted befor the stop codon of mouse Tie1 gene via homologous recombination to establish a tamoxifen inducible Tie1-Cre tool stain. This strain can be used to knockout target gene in Tie1+ cells when crossed with mice which carry loxp sites flanking target gene.

Mice

Csf2rb2-2A-Cre

Strain Name：C57BL/6Smoc-Csf2rb2em1(2A-Cre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210001
Validation Data：Presence

2A-Cre expression cassette was knocked into the Csf2rb2 gene. Csf2rb2 is also known as colony stimulating factor 2 receptor. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. The gene product has been involved in the modulation of memory.

Mice

Amhr2-IRES-CreERT2

Strain Name：C57BL/6Smoc-Amhr2em(IRES-2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-204995

IRES-2A-CreERT2 expression cassette was knocked into the Amhr2 gene via CRISPR/Cas9 mediated recombination.

Mice

Chga-CreERT2

Strain Name：C57BL/6Smoc-Chgaem(CreERT2-Wpre-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-204993
Validation Data：Presence

CreERT2-Wpre-pA expression cassette was knocked into the Chga gene.

Mice

Mesp1-CreERT2

Strain Name：C57BL/6Smoc-Mesp1em(CreERT2-Wpre-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215087

CreERT2-Wpre-pA expression cassette was knocked into the Mesp1 gene .

Mice

Meox1-Dre

Strain Name：C57BL/6Smoc-Meox1em1(Dre-Wpre-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200174

A Dre-Wpre-polyA expression cassette was knocked into the Meox1 gene start codon site.

Mice

R26-CreERT2

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-CreERT2-Rox-WPRE-Rox-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200041
Validation Data：Presence

These mice harbor a SA-FRT-2xpolyA-CAG-FRT-CreERT2-Rox-WPRE-Rox-polyA cassette in the Rosa26 locus generated by homologous recombination. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in multiple tissues after tamoxifen treatment.

Mice

hPD-1/hCD28

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Cd28tm2(hCD28)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000097

hPD-1(NM-HU-00015) was crossed with hCD28(NM-HU-190011) to generate hPD-1/hCD28.

Mice

Il7r-Cre

Strain Name：C57BL/6Smoc-Il7rem1(Cre-Wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200306
Validation Data：Presence

Cre-Wpre-pA expression cassette was knocked into the Il7r gene start codon site.

Mice

Il17b-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il17bem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00029

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il17b.

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