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Models

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Cells

MC38-hCD73

Strain Name:MC38-Nt5eem1(hCD73)/Smoc
Strain State : Validation of tumorigenic capacity completed |  Cat. NO.:NM-S13-TM03

The endogenous mouse Nt5e(also known as Cd73) gene was replaced by human CD73 gene. 

Cells

MC38-hPD-L1

Strain Name:MC38-Cd274em1(hPDL1)/Smoc
Strain State : Validation of pharmacodynamic assays completed |  Cat. NO.:NM-S13-TM01

The endogenous mouse Cd274(also known as PD-l1) gene was replaced by human PDL1 gene.

Cells

B16F10-hPD-L1

Strain Name:B16F10-Cd274em1(hPDL1)/Smoc
Strain State : Validation of tumorigenic capacity completed |  Cat. NO.:NM-S31A-TM01

The endogenous mouse Cd274(also known as PD-l1)  gene was replaced by human PDL1 gene. 

Cells

CT26-hPD-L1

Strain Name:CT26-Cd274em1(hPDL1)/Smoc
Strain State : Validation of tumorigenic capacity completed |  Cat. NO.:NM-S24A-TM01

The endogenous mouse Cd274(also known as  PD-L1)  gene was replaced by human CD274 gene. 

Cells

Hepa1-6-hPD-L1

Strain Name:Hepa1-6-Cd274em1(hPD-L1)Smoc
Strain State : Validation of tumorigenic capacity completed |  Cat. NO.:NM-GA02-TM01

The endogenous mouse Cd274(also known as PD-l1) gene was replaced by human PDL1 gene.

Cells

LLC1/LL2-hPD-L1

Strain Name:LLC1/LL2-Cd274em1(hCD274)Smoc
Strain State : Validation of tumorigenic capacity completed |  Cat. NO.:NM-S30A-TM01

The endogenous mouse Cd274(also known as PD-l1) gene was replaced by human PDL1 gene.

Cells

MC38-hCD47/hPD-L1

Strain Name:MC38-Cd274em1(hPDL1)Cd47em1(hCD47)/Smoc
Strain State : Validation of pharmacodynamic assays completed |  Cat. NO.:NM-S13-TM07

The endogenous mouse Cd274(also known as PD-l1)  and Cd47 gene was replaced by human PDL1 and CD47 gene.

Cells

MC38-hCD47-hCLDN18.2-hEGFR

Strain Name:MC38-hCD47-hCLDN18.2-hEGFR
Strain State : Validation of tumorigenic capacity completed |  Cat. NO.:NM-S13-TM73

The MC38-hCD47/hCLDN18.2/hEGFR cell line is the MC38 colon cancer tumor cell line expressing human CD47, human CLAUDIN18.2 gene and human EGFR gene. 

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