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Models

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Mice

Igl-KO

Strain Name:C57BL/6Smoc-Iglem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-191198

All genes between Gm10088 and Iglv2 were deleted to generate Igl knockout mice.

Mice

NMG

Strain Name:NOD.Cg-PrkdcscidIl2rgem1Smoc
Strain State:Repository Live | Cat. NO.:NM-NSG-001

Prkdc and Il2rg genes were both knocked-out in NOD mice.  Lacking mature T, B and NK cells Low immune rejection against human cells and tissues Good tumorigenicity so that a small number of cells can form tumors. Significant improvement in the survival of transplanted human cells and tissues Suitable for the transplantation of human hematopoietic stem cells and the preparation of humanized mouse models Suitable as the carrier mice for the transplantation of heterologous cells and tissues

Mice

Igk/Igl-KO

Strain Name:C57BL/6Smoc-IgkemIglem1Smoc
Strain State:Developing | Cat. NO.:NM-KO-241950

Igk and Igl genes were deleted to generate Igk/Igl knockout mice.

Mice

Rag2/IL2rg-KO/hCD40

Strain Name:C57BL/6Smoc-Cd40em1(hCD40)Rag2em1Il2rgem1/Smoc
Strain State:Developing | Cat. NO.:NM-HU-2000112

The Rag2 and Il2rg genes of the CD40 humanized mouse were deleted.

Mice

Rag2/IL2rg-KO/hSIRPA(2)/hCD47

Strain Name:C57BL/6Smoc-Sirpaem1(hSIRPA)Cd47em1(hCD47)Rag2em1Il2rgem1/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000019

The Rag2 and Il2rg genes of the hSIRPA(2)/hCD47 mouse were deleted.

Mice

hCSF1/hCSF1R(BALB/c)

Strain Name:BALB/cAnSmoc-Csf1tm2(CSF1)Csf1rem3(hCSF1R)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220016

The endogenous mouse Csf1 and Csf1r genes was replaced respectively by human CSF1 and CSF1R genes.

Mice

hIL5/hIL5R(2)

Strain Name:C57BL/6Smoc-Il5tm3(hIL5)Il5raem2(hIL5RA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-220010

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(3)(Stock No.NM-HU-220011) function similarly to hIL5/hIL5R(2) mice, for more detailed information please contact our technical advisor.

Mice

hIL5/hIL5R(3)

Strain Name:C57BL/6Smoc-Il5tm3(hIL5)Il5raem3(hIL5RA)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220011

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(2)(Stock No.NM-HU-220010) function similarly to hIL5/hIL5R(3) mice, for more detailed information please contact our technical advisor.

Mice

Bglap/Bglap2-KO(2)

Strain Name:C57BL/6Smoc-BglapemBglap2em2Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-231113

The exon 4 of Bglap and exon 1-4 of Bglap2 genes were deleted to generate Bglap and Bglap2 knockout mouse.

Mice

Sprr2a-KO

Strain Name:C57BL/6Smoc-Sprr2a1emSprr2a2emSprr2a3em1Smoc
Strain State:Developing | Cat. NO.:NM-KO-241703

The exon 1-exon 2 of Sprr2a1, exon 1-exon 2 of Sprr2a2 and exon 1-exon 2 of Sprr2a3 genes were deleted to generate Sprr2a1, Sprr2a2 and Sprr2a3 knockout mouse.

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