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Models

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Mice

hPD-L1/hCTLA-4

Strain Name：C57BL/6Smoc-Ctla4tm1(hCTLA4)Cd274tm1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00102
Validation Data：Presence

hPD-L1(NM-HU-00062) was crossed with hCTLA4(NM-HU-00014)to generate hPD-1/hCTLA4 mice

Mice

hDDR1

Strain Name：C57BL/6Smoc-Ddr1tm3(hDDR1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225086
Validation Data：Presence

The endogenous mouse Ddr1 gene was replaced by human DDR1 gene.

Mice

hPVRL2

Strain Name：C57BL/6Smoc-Nectin2tm1(hNECTIN2)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000084
Validation Data：Presence

The endogenous mouse Nectin2 gene was replaced by human PVRL2 gene.

Mice

AA467197-Flox

Strain Name：C57BL/6Smoc-AA467197em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253746

These mice carry loxP sites flanking exon 1-3 of AA467197 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of AA467197 gene.

Mice

hAPOE3

Strain Name：C57BL/6Smoc-Apoetm3(hAPOE3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190003
Validation Data：Presence

This APOE3 humanized mouse model was established by replacing the mouse Apoe gene coding exons and introns with the human APOE3 corresponding sequence by homologous recombination.

Mice

Casp8-Flox

Strain Name：C57BL/6Smoc-Casp8em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-190003

These Casp8 flox mice possess loxP sites flanking exons 4. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

Slc6a3-IRES-Cre

Strain Name：C57BL/6Smoc-Slc6a3em1(IRES-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200092
Validation Data：Presence

A IRES-iCre expression cassette was knocked into the Slc6a3 gene stop codon site.

Mice

A4gnt-Flox

Strain Name：C57BL/6Smoc-A4gntem1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253848

These mice carry loxP sites flanking exon 1-2 of A4gnt gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A4gnt gene.

Mice

hITGB1

Strain Name：C57BL/6Smoc-Itgb1tm1(hITGB1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225040
Validation Data：Presence

The endogenous mouse Itgb1 gene was replaced by human ITGB1 gene.

Mice

hDMPK

Strain Name：C57BL/6Smoc-Dmpktm1(hDMPK)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225084
Validation Data：Presence

The endogenous mouse Dmpk gene was replaced by human DMPK gene.

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