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Mice

hIGHG4

Strain Name：C57BL/6Smoc-Ighg1tm1(hIGHG4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225092
Validation Data：Presence

The endogenous mouse Ighg1 gene was replaced by human IGHG4 gene.

Mice

Gad1-2A-eGFP

Strain Name：C57BL/6Smoc-Gad1em(2A-eGFP)Smoc
Strain State：Developing | Cat. NO.：NM-KI-220179

2A-eGFP expression cassette was knocked into the Gad1 gene stop codon site.

Mice

hFCGR2B/h4-1BB(2)

Strain Name：C57BL/6Smoc-Fcgr2btm2(FCGR2B)Tnfrsf9tm2(TNFRSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210352
Validation Data：Presence

hFCGR2B(NM-HU-2000010) was crossed with h4-1BB (NM-HU-190077) to generate hFCGR2B/h4-1BB mice.

Mice

hIFNGR1/hIFNGR2

Strain Name：C57BL/6Smoc-Ifngr1tm3(hIFNGR1)Ifngr2tm(hIFNGR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220003
Validation Data：Presence

hIFNGR1(NM-HU-190076) was crossed with hIFNGR2(NM-HU-215010) to generate hIFNGR1/hIFNGR2 mice.

Mice

hPD-1/hTIM3

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Havcr2tm1(hHAVCR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00103
Validation Data：Presence

hPD-1(NM-HU-00015) was crossed with hTIM3(NM-HU-00054)to generate hPD-1/hTIM3 mice

Mice

Brca1-Flox

Strain Name：C57BL/6Smoc-Brca1tm1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-18007

These Brca1 flox mice possess loxP sites flanking exons 5 . When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

R26-CAG-LSL-hHER2-IRES-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(SA-2xpolyA-CAG-LSL-HER2-luciferase-EGFP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190008

A SA-2xpolyA-CAG-LSL-HER2-IRES-Luciferase-2A-EGFP-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the HER2 protein.

Mice

hMELTF

Strain Name：C57BL/6Smoc-Meltftm(hMELTF)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215011
Validation Data：Presence

The endogenous mouse Meltf gene was replaced by human MELTF gene.

Mice

hPSGL-1(2)

Strain Name：C57BL/6Smoc-Selplgtm2(hSELPLG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210026
Validation Data：Presence

The endogenous mice Selplg gene was completely or partially replaced by human SELPLG gene via CRISPR/Cas9 mediated recombination.

Mice

hPD-1/hSTING

Strain Name：C57BL/6Smoc-Tmem173tm1(hTMem173)Pdcd1tm1(hPDCD1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000104

hPD-1(NM-HU-00015) was crossed with hSTING(NM-HU-190036) to generate hPD-1/hSTING.

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