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Models

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Mice

hIl5

Strain Name：C57BL/6Smoc-Il5tm3(hIL5)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190001
Validation Data：Presence

This IL5 humanized mouse model was established by replacing the mouse Il5 gene coding exons and introns with the human TLR9 corresponding sequence by homologous recombination.

Mice

Trp63-CreERT2

Strain Name：C57BL/6Smoc-Trp63em(CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225021
Validation Data：Presence

A CreERT2-Wpre-polyA expression cassette was knocked into the exon4 of Trp63 gene via CRISPR/Cas mediated recombination.

Mice

Myf6-CreERT2

Strain Name：C57BL/6Smoc-Myf6em1(CreERT2-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200125
Validation Data：Presence  |  Publications：1piece

A CreERT2-pA expression cassette was knocked into the Myf6 gene start codon site. Myf6 (myogenic factor 6) is a DNA-binding protein involved in muscle development. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Myf6.

Mice

Sox10-2A-Cre

Strain Name：C57BL/6Smoc-Sox10em(2A-Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220066
Validation Data：Presence

2A-Cre expression cassette was knocked into the Sox10 gene stop codon site. The target gene is associated with pigment, and heterozygotes are recommended for mating in breeding.

Mice

hIL18BP

Strain Name：C57BL/6Smoc-Il18bptm1(hIL18BP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210039
Validation Data：Presence

The endogenous mice Il18bp gene was replaced by human IL18BP gene.

Mice

Xcr1-IRES-Cre

Strain Name：C57BL/6Smoc-Xcr1em1(IRES-iCre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200237
Validation Data：Presence

A IRES-iCre expression cassette was knocked into the Xcr1 gene stop codon site.

Mice

Tmem119-IRES-Cre

Strain Name：C57BL/6Smoc-Tmem119em1(IRES-Cre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-225007
Validation Data：Presence

IRES-Cre expression cassette was knocked into the Tmem119 gene stop codon site.

Mice

Trp53-Flox

Strain Name：C57BL/6Smoc-Trp53tm2(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-18005
Publications：1piece

These Trp53 flox mice possess loxP sites flanking exons 5-7 via ESC targeting. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

hTNFR2/hIL2RA

Strain Name：C57BL/6Smoc-Tnfrsf1btm2(hTNFRSF1B)Il2ratm1(hIL2RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210408

hTNFRSF1B(NM-HU-190010) was crossed with hIL2RA(NM-HU-190064) to generate hTNFRSF1B/hIL2RA mice.

Mice

hHER3

Strain Name：C57BL/6Smoc-Erbb3tm1(hERBB3)Smoc
Strain State：Developing | Cat. NO.：NM-HU-200234

The endogenous mice Erbb3 gene was replaced by human HER3 gene.

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