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Models

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Mice

hCFTR

Strain Name:C57BL/6Smoc-Cftrtm1(hCFTR)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-225060
Validation Data:Presence

The endogenous mouse Cftr gene was replaced by human CFTR gene.

Mice

Mertk-KO

Strain Name:C57BL/6Smoc-Mertkem1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-200362

Exon 2 of Mertk gene was deleted to generate Mertk knockout mice.

Mice

MHC Class II (I-A/I-E) -KO

Strain Name:C57BL/6Smoc-H2-Ab1em1H2-Aaem1 H2-Eb1em1H2-Eb2em1H2-Ea-ps em1 Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-18032
Validation Data:Presence

All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models. These MHC class II molecule-deficient mice were on the C57BL/6J genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins.

Mice

hTLR2

Strain Name:C57BL/6Smoc-Tlr2tm2(hTLR2)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190066
Validation Data:Presence

The endogenous mouse Tlr2 gene was replaced by human TLR2 gene.

Mice

hTSLP/hIL17RA

Strain Name:C57BL/6Smoc-Tslptm2(hTSLP)Il17rtm1(hIL17R)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200269

hTSLP(NM-HU-2000064)was crossed with hIL17R(NM-HU-190049)to generate hTSLP/hIL17RA mice

Mice

Cartpt-IRES-Cre

Strain Name:C57BL/6Smoc-Cartptem1(IRES-iCre)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200094
Validation Data:Presence  |  Publications:1piece

A IRES-iCre expression cassette was knocked into the Cartpt gene stop codon site.

Mice

hNCR3

Strain Name:C57BL/6Smoc-Ncr1tm1(hNCR3)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-215066
Validation Data:Presence

The endogenous mouse Ncr1 gene was replaced by human NCR3 gene.

Mice

hPD-L1/hCD27(2)

Strain Name:C57BL/6Smoc-Cd274tm1(hPD-L1)Cd27tm3(hCD27)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200274

hPD-L1(NM-HU-00062) was crossed with hCD27(2)(NM-HU-190035)to generate hPD-L1/hCD27(2) mice.While hPD-L1/hCD27 (Stock No.NM-HU-18023) have been pulled from shelves for some reasons.

Mice

hIL31

Strain Name:C57BL/6Smoc-Il31tm2(IL31)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200008
Validation Data:Presence

The endogenous mouse Il31 gene was replaced by human IL31 gene.

Mice

hGDF15

Strain Name:C57BL/6Smoc-Gdf15tm(hGDF15)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-215002
Validation Data:Presence

The endogenous mice Gdf15 gene was replaced by human GDF15 gene.

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