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Models

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Mice

hCD93

Strain Name：C57BL/6Smoc-Cd93em1(hCD93)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215065

The endogenous mouse Cd93 gene was replaced by human CD93 gene.

Mice

A2ml1-Flox

Strain Name：C57BL/6Smoc-A2ml1em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of A2ml1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A2ml1 gene.

Mice

hPD-1/hTIM3

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Havcr2em1(hHAVCR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00103

hPD-1(NM-HU-00015) was crossed with hTIM3(NM-HU-00054)to generate hPD-1/hTIM3 mice

Mice

hDLL4

Strain Name：C57BL/6Smoc-Dll4tm1(hDLL4)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000020

The endogenous mouse Dll4 gene was replaced by human DLL4 gene.

Mice

Shh-CreERT2

Strain Name：C57BL/6Smoc-Shhem1(CreERT2-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200145

A  CreERT2-WPRE-polyA expression cassette was knocked into the Shh gene start codon site. Expression of Shh-CreERT2 may be "leaky" at 1-month-old mice without tamoxifen.

Mice

a-IRES-Cre

Strain Name：C57BL/6Smoc-atm1(Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200027

A IRES-Cre expression cassette was knocked into the a gene stop codon site via ESC targeting. Male mice with a germline Cre leak expression condition, please use female mice and flox mice for breeding crosses. References are available, please see the website for details.

Mice

hCXCR5

Strain Name：C57BL/6Smoc-Cxcr5em(hCXCR5)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-215007

The endogenous mice Cxcr5 gene was replaced by human CXCR5 gene.

Mice

Ascl1-CreERT2

Strain Name：C57BL/6Smoc-Ascl1em1(CreERT2-Wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200207

A CreERT2-Wpre-pA expression cassette was knocked into the Ascl1 gene start codon site.

Mice

hPTPN1

Strain Name：C57BL/6Smoc-Ptpn1tm1(hPTPN1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225059

The endogenous mouse Ptpn1 gene was replaced by human PTPN1 gene.

Mice

hIl5

Strain Name：C57BL/6Smoc-Il5tm3(hIL5)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190001

This IL5 humanized mouse model was established by replacing the mouse Il5 gene coding exons and introns with the human TLR9 corresponding sequence by homologous recombination.

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