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Models

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Mice

hMAPT

Strain Name：C57BL/6Smoc-Mapttm1(hMAPT)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200116
Validation Data：Presence

The endogenous mouse Mapt gene was replaced by human MAPT gene.

Mice

App-KO

Strain Name：C57BL/6Smoc-Appem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190444

exon 3 of App gene was deleted to generate App knockout mice.

Mice

hPSMA

Strain Name：C57BL/6Smoc-Folh1tm1(hPSMA-Wpre-PA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200240
Validation Data：Presence

The endogenous mice Folh1 gene was replaced by human PSMA gene.

Mice

hIL15RA

Strain Name：C57BL/6Smoc-Il15ratm1(hIL15RA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-215070

The endogenous mouse Il15ra gene was replaced by human IL15RA gene.

Mice

hCTLA-4/h4-1BB(2)

Strain Name：C57BL/6Smoc-Ctla4tm1(hCTLA4)Tnfrsf9tm2(TNFRSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210355

hCTLA4(NM-HU-00014) was crossed with h4-1BB(2)(NM-HU-190077）to generate hCTLA4/h4-1BB(2) mice.

Mice

Slc17a6-IRES-Cre

Strain Name：C57BL/6Smoc-Slc17a6em1(IRES-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200087
Validation Data：Presence  |  Publications：1piece

A IRES-iCre expression cassette was knocked into the Slc17a6 gene stop codon site.

Mice

hCD3E/hCD28

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E))Cd28tm2(hCD28)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210233

hCD3E(NM-HU-00114) was crossed with hCD28(NM-HU-190011) to generate hCD3E/hCD28 mice.

Mice

hTLR4

Strain Name：C57BL/6Smoc-Tlr4tm2(hTLR4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000025
Validation Data：Presence

The endogenous mouse Tlr4 gene was replaced by human TLR4 gene.

Mice

hCD3E/hCD38(2)

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E))Cd38tm2(hCD38)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210234

hCD3E(NM-HU-00114) was crossed with hCD38(2)(NM-HU-190059) to generate hCD3E/hCD38(2) mice.

Mice

hIL2RG

Strain Name：C57BL/6Smoc-Il2rgtm1(IL2RG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200007

The endogenous mouse Il2rg gene was replaced by human IL2RG gene.

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